Integration of genomics, proteomics, and imaging for cardiac stem cell therapy

被引:0
|
作者
Hyung J. Chun
Kitch O. Wilson
Mei Huang
Joseph C. Wu
机构
[1] Stanford University School of Medicine,Department of Medicine, Division of Cardiology
[2] Stanford University School of Medicine,Molecular Imaging Program at Stanford, Department of Radiology
关键词
Stem cell; Coronary artery disease; Heart failure; Reporter gene imaging; Proteomics; Gene expression profiling;
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学科分类号
摘要
Cardiac stem cell therapy is beginning to mature as a valid treatment for heart disease. As more clinical trials utilizing stem cells emerge, it is imperative to establish the mechanisms by which stem cells confer benefit in cardiac diseases. In this paper, we review three methods—molecular cellular imaging, gene expression profiling, and proteomic analysis—that can be integrated to provide further insights into the role of this emerging therapy.
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页码:20 / 26
页数:6
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