The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington’s disease brain

被引：0
|
作者：
Filisia Agus
Diego Crespo
Richard H. Myers
Adam Labadorf
机构：
[1] Bioinformatics Nexus,
[2] Boston University,undefined
[3] Bioinformatics Program,undefined
[4] Boston University,undefined
[5] Department of Neurology,undefined
[6] Boston University School of Medicine,undefined
来源：
BMC Medical Genomics | / 12卷
关键词：
Huntington’s disease; Neurodegeneration; Bioinformatics; High throughput mRNA sequencing; Differential expression; Machine learning;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases
    Handley, Renee R.
    Reid, Suzanne J.
    Brauning, Rudiger
    Maclean, Paul
    Mears, Emily R.
    Fourie, Imche
    Patassini, Stefano
    Cooper, Garth J. S.
    Rudiger, Skye R.
    McLaughlan, Clive J.
    Verma, Paul J.
    Gusella, James F.
    MacDonald, Marcy E.
    Waldvogel, Henry J.
    Bawden, C. Simon
    Faull, Richard L. M.
    Snell, Russell G.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (52) : E11293 - E11302
  • [42] An image-based model of brain volume biomarker changes in Huntington's disease
    Wijeratne, Peter A.
    Young, Alexandra L.
    Oxtoby, Neil P.
    Marinescu, Razvan V.
    Firth, Nicholas C.
    Johnson, Eileanoir B.
    Mohan, Amrita
    Sampaio, Cristina
    Scahill, Rachael I.
    Tabrizi, Sarah J.
    Alexander, Daniel C.
    ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY, 2018, 5 (05): : 570 - 582
  • [43] Progressive transcriptional changes in metabolic genes and altered fatbody homeostasis in Drosophila model of Huntington’s disease
    Akanksha Singh
    Namita Agrawal
    Metabolic Brain Disease, 2022, 37 : 2783 - 2792
  • [44] Cognition in relation to metabolic changes in the brain of preclinical mutation carriers of Huntington's disease
    Dekker, M.
    van Oostrom, J.
    Jurgens, C.
    Witjes-Ane, M. -N
    Spikman, J.
    Roos, R.
    Leenders, N.
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2008, 79 : A20 - A20
  • [45] Progressive transcriptional changes in metabolic genes and altered fatbody homeostasis in Drosophila model of Huntington's disease
    Singh, Akanksha
    Agrawal, Namita
    METABOLIC BRAIN DISEASE, 2022, 37 (08) : 2783 - 2792
  • [46] The dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell model
    van Hagen, Martijn
    Piebes, Diewertje G. E.
    de Leeuw, Wim C.
    Vuist, Ilona M.
    van Roon-Mom, Willeke M. C.
    Moerland, Perry D.
    Verschure, Pernette J.
    BMC GENOMICS, 2017, 18
  • [47] The dynamics of early-state transcriptional changes and aggregate formation in a Huntington’s disease cell model
    Martijn van Hagen
    Diewertje G. E. Piebes
    Wim C. de Leeuw
    Ilona M. Vuist
    Willeke M. C. van Roon-Mom
    Perry D. Moerland
    Pernette J. Verschure
    BMC Genomics, 18
  • [48] Human brain PET imaging of PDE10A in Parkinson's and Huntington's disease
    Ahmad, R. U.
    Bourgeois, S.
    Postnov, A.
    Schmidt, M. E.
    Bormans, G.
    Vandenberghe, W.
    Van Laere, K.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2013, 40 : S231 - S231
  • [49] Chromogranins in human brain and their changes in Alzheimer's disease
    Marksteiner, J
    Kaufmann, W
    Mahata, M
    Mahata, SK
    Saria, A
    Fischer-Colbrie, R
    Humpel, C
    JOURNAL OF NEUROCHEMISTRY, 2005, 94 : 185 - 186
  • [50] Lifespan Changes of the Human Brain In Alzheimer's Disease
    Coupe, Pierrick
    Manjon, Jose Vicente
    Lanuza, Enrique
    Catheline, Gwenaelle
    SCIENTIFIC REPORTS, 2019, 9 (1)
12345