The Impact of a Mobile Gaming Intervention to Increase Adherence to Pre-exposure Prophylaxis

被引:0
|
作者
Laura Whiteley
Lacey Craker
Kayla K. Haubrick
Trisha Arnold
Leandro Mena
Elizabeth Olsen
Larry K. Brown
机构
[1] Brown University,Residence Training Program, Warren Alpert Medical School
[2] Rhode Island Hospital,Department of Psychiatry
[3] University of Mississippi Medical Center,Department of Population Health Science
[4] University of Mississippi Medical Center,Division of Infectious Diseases
来源
AIDS and Behavior | 2021年 / 25卷
关键词
Pre-exposure prophylaxis (PrEP); Adherence; Men who have sex with men (MSM); Mobile technology intervention;
D O I
暂无
中图分类号
学科分类号
摘要
Pre-exposure prophylaxis is effective in preventing HIV, but data show that its effectiveness is compromised by suboptimal adherence. This randomized controlled trial (n = 69) tested the impact of an iPhone game, Viral Combat, on PrEP adherence over 24 weeks. Tenofovir-diphosphate in red blood cells was collected as a biological outcome of adherence. At 24-weeks, intervention participants were 3.75 (95% CI: 1.20–11.77; p = 0.02) times as likely to engage in optimal PrEP dosing compared to controls. Viral Combat showed preliminary efficacy in improving PrEP adherence for diverse young men who have sex with men.
引用
收藏
页码:1884 / 1889
页数:5
相关论文
共 50 条
  • [1] The Impact of a Mobile Gaming Intervention to Increase Adherence to Pre-exposure Prophylaxis
    Whiteley, Laura
    Craker, Lacey
    Haubrick, Kayla K.
    Arnold, Trisha
    Mena, Leandro
    Olsen, Elizabeth
    Brown, Larry K.
    [J]. AIDS AND BEHAVIOR, 2021, 25 (06) : 1884 - 1889
  • [2] A Mobile Gaming Intervention for Persons on Pre-Exposure Prophylaxis: Protocol for Intervention Development and Randomized Controlled Trial
    Whiteley, Laura
    Olsen, Elizabeth
    Mena, Leandro
    Haubrick, Kayla
    Craker, Lacey
    Hershkowitz, Dylan
    Brown, Larry K.
    [J]. JMIR RESEARCH PROTOCOLS, 2020, 9 (09):
  • [3] Creating a Theoretically Grounded Gaming App to Increase Adherence to Pre-Exposure Prophylaxis: Lessons From the Development of the Viral Combat Mobile Phone Game
    Whiteley, Laura
    Mena, Leandro
    Craker, Lacey K.
    Healy, Meredith Garver
    Brown, Larry K.
    [J]. JMIR SERIOUS GAMES, 2019, 7 (01):
  • [4] Pre-exposure prophylaxis adherence and discontinuation at an urban pre-exposure prophylaxis program in Atlanta, Georgia
    Yacout, Hiba
    Smith, Bradley L.
    Foster, Shelbie
    Lora, Meredith
    Niles-Carnes, Larisa V.
    Zheng, Ziduo
    Kundu, Suprateek
    Cantos, Valeria D.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, 2023, 6 (06): : 576 - 580
  • [5] ADHERENCE TO ORAL PRE-EXPOSURE PROPHYLAXIS INTERVENTION BY TRANSGENDER WOMEN: A SYSTEMATIC REVIEW
    Eduardo Moncayo, Jorge
    Perez-Arizabaleta, Maria Del Mar
    Villegas-Trujillo, Lina Maria
    Rodriguez-Ortiz, Alejandra
    [J]. AIDS EDUCATION AND PREVENTION, 2023, 35 (05) : 362 - 375
  • [6] A systematic evaluation of mobile apps to improve the uptake of and adherence to HIV pre-exposure prophylaxis
    Sharpe, J. Danielle
    Kamara, Mustapha T.
    [J]. SEXUAL HEALTH, 2018, 15 (06) : 587 - 594
  • [7] Individualized Adherence Benchmarks for HIV Pre-Exposure Prophylaxis
    Ibrahim, Mustafa E.
    Castillo-Mancilla, Jose R.
    Yager, Jenna
    Brooks, Kristina M.
    Bushman, Lane
    Saba, Laura
    Kiser, Jennifer J.
    MaWhinney, Samantha
    Anderson, Peter L.
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 2021, 37 (06) : 421 - 428
  • [8] Comparing Self-Report Pre-Exposure Prophylaxis Adherence Questions to Pharmacologic Measures of Recent and Cumulative Pre-Exposure Prophylaxis Exposure
    Blumenthal, Jill
    Pasipanodya, Elizabeth C.
    Jain, Sonia
    Sun, Shelly
    Ellorin, Eric
    Morris, Sheldon
    Moore, David J.
    [J]. FRONTIERS IN PHARMACOLOGY, 2019, 10
  • [9] Understanding Pre-Exposure Prophylaxis Adherence in Young Women in Kenya
    Haberer, Jessica E.
    Mugo, Nelly
    Bukusi, Elizabeth Ann
    Ngure, Kenneth
    Kiptinness, Catherine
    Oware, Kevin
    Garrison, Lindsey E.
    Musinguzi, Nicholas
    Pyra, Maria
    Valenzuela, Susie
    Thomas, Katherine K.
    Anderson, Peter L.
    Thirumurthy, Harsha
    Baeten, Jared M.
    [J]. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2022, 89 (03) : 251 - 260
  • [10] High Adherence to HIV Pre-Exposure Prophylaxis among Veterans
    Misha Huang
    Wenhui Liu
    Mary E. Plomondon
    Allan V. Prochazka
    Mary T. Bessesen
    [J]. Journal of General Internal Medicine, 2018, 33 : 253 - 255