The Impact of a Mobile Gaming Intervention to Increase Adherence to Pre-exposure Prophylaxis

被引：10
|
作者：
Whiteley, Laura [1 ]
Craker, Lacey [2 ]
Haubrick, Kayla K. [2 ]
Arnold, Trisha [1 ]
Mena, Leandro [3 ,4 ]
Olsen, Elizabeth [1 ]
Brown, Larry K. [1 ,2 ]
机构：
[1] Brown Univ, Warren Alpert Med Sch, Residence Training Program, 345 Blackstone Blvd, Providence, RI 02906 USA
[2] Rhode Isl Hosp, Dept Psychiat, Providence, RI USA
[3] Univ Mississippi, Med Ctr, Dept Populat Hlth Sci, Jackson, MS 39216 USA
[4] Univ Mississippi, Med Ctr, Div Infect Dis, Jackson, MS 39216 USA
来源：
AIDS AND BEHAVIOR | 2021年 / 25卷 / 06期
关键词：
Pre-exposure prophylaxis (PrEP); Adherence; Men who have sex with men (MSM); Mobile technology intervention;
D O I：
10.1007/s10461-020-03118-3
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Pre-exposure prophylaxis is effective in preventing HIV, but data show that its effectiveness is compromised by suboptimal adherence. This randomized controlled trial (n = 69) tested the impact of an iPhone game, Viral Combat, on PrEP adherence over 24 weeks. Tenofovir-diphosphate in red blood cells was collected as a biological outcome of adherence. At 24-weeks, intervention participants were 3.75 (95% CI: 1.20-11.77; p = 0.02) times as likely to engage in optimal PrEP dosing compared to controls. Viral Combat showed preliminary efficacy in improving PrEP adherence for diverse young men who have sex with men.
引用
收藏
页码：1884 / 1889
页数：6
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