Synthesis of Polyfunctionalized Hexahydropyrimidines

被引：0
|
作者：
A. G. Badamshin
D. R. Latypova
V. A. Dokichev
机构：
[1] Russian Academy of Sciences,Ufa Institute of Chemistry, Ufa Research Center
[2] Ufa State Aviation Technical University,undefined
来源：
Russian Journal of Organic Chemistry | 2019年 / 55卷
关键词：
synthesis; alkyl 5-acetylhexahydropyrimidine-5-carboxylates; ammonia; hydrazine hydrate; lithium aluminum hydride;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The reactions of alkyl 5-acetylhexahydropyrimidine-5-carboxylates with ammonia, hydrazine hydrate, and lithium aluminum hydride were used to synthesize hexahydropyrimidine derivatives containing pharmacophoric 1,3-propylenediamine and 1,3-propanolamine fragments.
引用
收藏
页码：168 / 173
页数：5
相关论文
共 50 条
  • [41] TETRAFORMYLTETRATHIAFULVALENE(TFTTF) - SYNTHESIS AND SOME USES AS A PRECURSOR OF POLYFUNCTIONALIZED TETRATHIAFULVALENES
    GORGUES, A
    BATAIL, P
    LECOQ, A
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1983, (08) : 405 - 406
  • [42] Synthesis of polyfunctionalized piperidone oxime ethers and their cytotoxicity on HeLa cells
    Parthiban, Paramasivam
    Pallela, Ramjee
    Kim, Se-Kwon
    Park, Dong Ho
    Jeong, Yeon Tae
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (22) : 6678 - 6686
  • [43] TETRAFORMYLTETRASELENAFULVALENE (TFTSEF) - SYNTHESIS AND SOME USES AS A PRECURSOR OF POLYFUNCTIONALIZED TETRASELENAFULVALENES
    SALLE, M
    GORGUES, A
    FABRE, JM
    BECHGAARD, K
    JUBAULT, M
    TEXIER, F
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1989, (20) : 1520 - 1521
  • [44] Synthesis of polyfunctionalized biphenyls as intermediates for a new class of liquid crystals
    Manka, JT
    Guo, FL
    Huang, JP
    Yin, HY
    Farrar, JM
    Sienkowska, M
    Benin, V
    Kaszynski, P
    JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (25): : 9574 - 9588
  • [45] One-pot synthesis of polyfunctionalized cyclic urea derivatives
    Fioravanti, S
    Marchetti, F
    Morreale, A
    Pellacani, L
    Tardella, PA
    ORGANIC LETTERS, 2003, 5 (07) : 1019 - 1021
  • [46] Asymmetric synthesis of alkaloids using polyfunctionalized chiral building blocks
    Davis, FA
    Chao, B
    Andemichael, YW
    Mohanty, PK
    Fang, TN
    Burns, DM
    Rao, A
    Szewczyk, JM
    HETEROATOM CHEMISTRY, 2002, 13 (05) : 486 - 492
  • [47] Novel syntheses of hexahydropyrimidines and tetrahydroquinazolines
    Katritzky, AR
    Singh, SK
    He, HY
    JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (09): : 3115 - 3117
  • [48] Recent developments in the enantioselective synthesis of polyfunctionalized pyran and chromene derivatives
    Sadek, Kamal Usef
    Mekheimer, Ramadan Ahmed H.
    Abd-Elmonem, Mohamed
    Abdel-Hameed, Afaf
    Elnagdi, Mohamed Hilmy
    TETRAHEDRON-ASYMMETRY, 2017, 28 (11) : 1462 - 1485
  • [49] Novel and convenient synthesis of polyfunctionalized quinolines, quinolones and their annulation reactions
    Wang, MX
    Liu, Y
    Huang, ZT
    TETRAHEDRON LETTERS, 2001, 42 (13) : 2553 - 2555
  • [50] Straightforward stereoselective synthesis of polyfunctionalized cyclohexenols using a multicomponent approach
    Basso, Andrea
    Banfi, Luca
    Guanti, Giuseppe
    Riva, Renata
    TETRAHEDRON, 2010, 66 (13) : 2390 - 2397
12345