Interaction of titanium dioxide nanoparticles with influenza virus

被引：91

作者：

Mazurkova N.A. ^{[1
,2
]}

Spitsyna Y.E. ^{[1
,4
]}

Shikina N.V. ^{[3
]}

Ismagilov Z.R. ^{[3
]}

Zagrebel'nyi S.N. ^{[1
]}

Ryabchikova E.I. ^{[1
,4
]}

机构：

[1] Novosibirsk State University, Novosibirsk 630090

[2] Vector State Scientific Center for Virology and Biotechnology, r.p. Kol'tsovo

[3] Boreskov Institute of Catalysis, Siberian Branch, Russian Academy of Sciences, Novosibirsk 630090

[4] Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk 630090

来源：

Nanotechnologies in Russia | 2010年 / 5卷 / 5-6期

基金：

俄罗斯基础研究基金会;

关键词：

Influenza; Influenza Virus; Virus Particle; Virus Envelope; Phosphotungstic Acid;

D O I：

10.1134/S1995078010050174

中图分类号：

学科分类号：

摘要：

Titanium dioxide (TiO2) in a suspension or absorbed on a film possesses bactericidal and virucidal properties caused by photocatalytic reactions. Our electron microscopic examinations showed that titanium dioxide nanoparticles destroyed the influenza virus after 30 min incubation. Virological studies revealed the inactivation of the influenza virus by TiO2, depending on the concentration of nanoparticles and the incubation period. The inactivation effect was observed when the incubation was performed in darkness, unlike the TiO2 suspension. We propose that the virus-inactivation properties of TiO2 are mainly based on the direct contact between nanoparticles and virus particles. © 2010 Pleiades Publishing, Ltd.

引用

页码：417 / 420

页数：3

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