Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells

被引:0
|
作者
Yan-Fang Tao
Jun Lu
Xiao-Juan Du
Li-Chao Sun
Xuan Zhao
Liang Peng
Lan Cao
Pei-Fang Xiao
Li Pang
Dong Wu
Na Wang
Xing Feng
Yan-Hong Li
Jian Ni
Jian Wang
Jian Pan
机构
[1] Children's Hospital of Soochow University,Department of Hematology and Oncology
[2] the 5th Hospital of Chinese PLA,Department of Gastroenterology
[3] Cancer Institute (Hospital),Department of Cell and Molecular Biology
[4] Chinese Academy of Medical Sciences,Institute of Clinical Medical Science
[5] Peking Union Medical College,Translational Research Center, Second Hospital
[6] Beijing Insititute for Drug Control,undefined
[7] China-Japan Friendship Hospital,undefined
[8] The Second Clinical School,undefined
[9] Nanjing Medical University,undefined
来源
BMC Cancer | / 12卷
关键词
YM155; SK-NEP-1; Survivin; Apoptosis; Real-time PCR array;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] YM155 kills quiescent (G0/G1) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1
    Ookura, Miyuki
    Yamauchi, Takahiro
    Ueda, Takanori
    Yagi, Hideki
    Yoshida, Akira
    CANCER SCIENCE, 2018, 109 : 1142 - 1142
  • [42] Synergistic cytotoxicity of decitabine and YM155 in leukemia cells through upregulation of SLC35F2 and suppression of MCL1 and survivin expression
    Jing-Ting Chiou
    Long-Sen Chang
    Apoptosis, 2024, 29 : 503 - 520
  • [43] YM155 enhances ABT-737-mediated apoptosis through Mcl-1 downregulation in Mcl-1-overexpressed cancer cells
    Seon Min Woo
    Kyoung-jin Min
    Bo Ram Seo
    Young Ho Seo
    Yong-Jin Jeong
    Taeg Kyu Kwon
    Molecular and Cellular Biochemistry, 2017, 429 : 91 - 102
  • [44] YM155 Down-Regulates Survivin and Induces P53 Up-Regulated Modulator of Apoptosis ( PUMA)-Dependent in Oral Squamous Cell Carcinoma Cells
    Yan, Xiang
    Su, Han
    MEDICAL SCIENCE MONITOR, 2017, 23 : 1963 - 1972
  • [45] Synergistic cytotoxicity of decitabine and YM155 in leukemia cells through upregulation of SLC35F2 and suppression of MCL1 and survivin expression
    Chiou, Jing-Ting
    Chang, Long-Sen
    APOPTOSIS, 2024, 29 (3-4) : 503 - 520
  • [46] Survivin Inhibitor YM-155 Sensitizes Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Resistant Glioma Cells to Apoptosis through Mcl-1 Downregulation and by Engaging the Mitochondrial Death Pathway
    Premkumar, Daniel R.
    Jane, Esther P.
    Foster, Kimberly A.
    Pollack, Ian F.
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2013, 346 (02): : 201 - 210
  • [47] Phase I safety and pharmacokinetic study of YM155, a potent selective survivin inhibitor, in combination with erlotinib in patients with EGFR TKI refractory advanced non-small cell lung cancer
    Shimizu, Toshio
    Nishio, Kazuto
    Sakai, Kazuko
    Okamoto, Isamu
    Okamoto, Kunio
    Takeda, Masayuki
    Morishita, Maiko
    Nakagawa, Kazuhiko
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2020, 86 (02) : 211 - 219
  • [48] Phase I safety and pharmacokinetic study of YM155, a potent selective survivin inhibitor, in combination with erlotinib in patients with EGFR TKI refractory advanced non-small cell lung cancer
    Toshio Shimizu
    Kazuto Nishio
    Kazuko Sakai
    Isamu Okamoto
    Kunio Okamoto
    Masayuki Takeda
    Maiko Morishita
    Kazuhiko Nakagawa
    Cancer Chemotherapy and Pharmacology, 2020, 86 : 211 - 219
  • [49] Sepantronium Bromide (YM155), A Small Molecule Survivin Inhibitor, Promotes Apoptosis by Induction of Oxidative Stress, Worsens the Behavioral Deficits and Develops an Early Model of Toxic Demyelination: In Vivo and In-Silico Study
    Reiszadeh-Jahromi, Samaneh
    Sepand, Mohammad-Reza
    Ramezani-sefidar, Samaneh
    Shahlaei, Mohsen
    Moradi, Sajad
    Yazdankhah, Meysam
    Sanadgol, Nima
    NEUROCHEMICAL RESEARCH, 2019, 44 (11) : 2482 - 2498
  • [50] Sepantronium Bromide (YM155), A Small Molecule Survivin Inhibitor, Promotes Apoptosis by Induction of Oxidative Stress, Worsens the Behavioral Deficits and Develops an Early Model of Toxic Demyelination: In Vivo and In-Silico Study
    Samaneh Reiszadeh-Jahromi
    Mohammad-Reza Sepand
    Samaneh Ramezani-sefidar
    Mohsen Shahlaei
    Sajad Moradi
    Meysam Yazdankhah
    Nima Sanadgol
    Neurochemical Research, 2019, 44 : 2482 - 2498