Design, synthesis, anticancer evaluation and docking studies of novel 2-(1-isonicotinoyl-3-phenyl-1H-pyrazol-4-yl)-3-phenylthiazolidin-4-one derivatives as Aurora-A kinase inhibitors

被引:0
|
作者
Meenu Beniwal
Neelam Jain
Sandeep Jain
Navidha Aggarwal
机构
[1] Bhagat Phool Singh Mahila Vishwavidyalaya,Department of Pharmaceutical Education & Research
[2] Khanpur Kalan,Department of Pharmaceutical Sciences
[3] Guru Jambheshwar University of Science and Technology,undefined
[4] MM College of Pharmacy,undefined
[5] Maharishi Markandeshwar (Deemed to be University),undefined
来源
BMC Chemistry | / 16卷
关键词
Aurora-A kinase; Pyrazole; Thiazolidin-4-one; Cell cycle arrest; MTT assay; Docking studies;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Synthesis and Anticancer Evaluation of 2-{4-[5-(5-Substituted arylpyrimidin-2-yl)-1H-pyrazol-3-yl]-phenyl}thiazolo[4,5-b]pyridine Derivatives
    Ch. P. Koteswara Rao
    T. B. Rao
    G. Kali Charan
    B. Srinu
    S. R. Maturi
    Russian Journal of General Chemistry, 2019, 89 : 1023 - 1028
  • [32] Synthesis and Anticancer Evaluation of 2-{4-[5-(5-Substituted arylpyrimidin-2-yl)-1H-pyrazol-3-yl]-phenyl}thiazolo[4,5-b]pyridine Derivatives
    Rao, Ch. P. Koteswara
    Rao, T. B.
    Charan, G. Kali
    Srinu, B.
    Maturi, S. R.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2019, 89 (05) : 1023 - 1028
  • [33] Synthesis, anticancer activity and molecular docking study of (E)-4-(3,4Dichlorophenyl)-2-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)-3,4- dihydronaphthalen-1(2H)-one derivatives
    Sadanandam, Kudikala
    Pinnoju, Prasad
    Manasa, S. K.
    Sarasija, Madderla
    CHEMICAL BIOLOGY LETTERS, 2024, 11 (01):
  • [34] Molecular Docking, Spectroscopic, and Computational Studies of 2-{3-(4-Chlorophenyl)-5-[4-(Propan-2-yl) Phenyl]-4, 5-Dihydro-1H-Pyrazol-1-yl}-1, 3-Thiazol-4(5H)-One
    Jayasudha, J.
    Balachandran, V.
    Narayana, B.
    POLYCYCLIC AROMATIC COMPOUNDS, 2022, 42 (05) : 2222 - 2244
  • [35] Synthesis and Antibacterial Activity of a New Series of 3-[3-(Substituted Phenyl)-1-Isonicotinoyl-1H-Pyrazol-5-yl]-2H-Chromen-2-one Derivatives
    Aragade, Prashant
    Maddi, Veeresh
    Khode, Suresh
    Palkar, Mahesh
    Ronad, Pradeepkumar
    Mamledesai, Shivalingarao
    Satyanarayana, Darbhamulla
    ARCHIV DER PHARMAZIE, 2009, 342 (06) : 361 - 366
  • [36] Synthesis, characterization, and biological properties of 2-((3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene) hydrazinecarboxamide
    Patel, J.D.
    Journal of Chemical and Pharmaceutical Research, 2013, 5 (01) : 200 - 204
  • [37] Synthesis, biological evaluation, and molecular docking studies of N-((1,3-diphenyl-1H-pyrazol-4-yl)methyl)aniline derivatives as novel anticancer agents
    Huang, Xian-Feng
    Lu, Xiang
    Zhang, Yong
    Song, Guo-Qiang
    He, Qi-Long
    Li, Qing-Shan
    Yang, Xian-Hui
    Wei, Yao
    Zhu, Hai-Liang
    BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 20 (16) : 4895 - 4900
  • [38] 4-{[(E)-(3,5-Dimethyl-1-phenyl-1H-pyrazol-4-yl)methylidene]amino}-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one
    Fun, Hoong-Kun
    Hemamalini, Madhukar
    Asiri, Abdullah M.
    Khan, Salman A.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O1602 - U838
  • [39] Design, synthesis of novel (Z)-2-(3-(4-((3-benzyl-2,4dioxothiazolidin-5-ylidene)methyl)-1-phenyl-1H-pyrazol-3-yl) phenoxy)-N-arylacetamide derivatives: Evaluation of cytotoxic activity and molecular docking studies
    Kolluri, Prashanth Kumar
    Gurrapu, Nirmala
    Subhashini, N. J. P.
    Putta, Shravani
    Singh, Surya Sathyanarayana
    Vani, Tamalapakula
    Manga, Vijjulatha
    JOURNAL OF MOLECULAR STRUCTURE, 2020, 1202
  • [40] SYNTHESIS OF SOME 2-(3-(4-ETHYLPHENYL)-1-PHENYL-1H-PYRAZOL-4-YL)) VINYL-4H-CHROMENE-4-ONES
    Thore, S. N.
    Gupta, Ashwini Kumar
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2010, 19 (04) : 329 - 332