Histone H4 lysine 16 acetylation breaks the genome's silence

被引：0
|
作者：
Wei-Jong Shia
Samantha G Pattenden
Jerry L Workman
机构：
[1] Stowers Institute for Medical Research,Department of Biochemistry and Molecular Biology
[2] Pennsylvania State University,undefined
来源：
Genome Biology | / 7卷
关键词：
Histone Modification; Histone Acetylation; Dosage Compensation; Acetylation State; Chromatin Decondensation;
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摘要：
Acetylation at histone H4 lysine 16 is involved in many cellular processes in organisms as diverse as yeast and humans. A recent biochemical study pinpoints this particular acetylation mark as a switch for changing chromatin from a repressive to a transcriptionally active state.
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