Association between APOE-ε4 allele and cognitive function is mediated by Alzheimer’s disease pathology: a population-based autopsy study in an admixed sample

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作者
Regina Silva Paradela
Alberto Fernando Oliveira Justo
Vítor Ribeiro Paes
Renata E. P. Leite
Carlos A. Pasqualucci
Lea T. Grinberg
Michel Satya Naslavsky
Mayana Zatz
Ricardo Nitrini
Wilson Jacob-Filho
Claudia Kimie Suemoto
机构
[1] University of São Paulo Medical School,Division of Geriatrics
[2] University of Sao Paulo Medical School,Department of Pathology
[3] University of California,Memory and Aging Center
[4] University of São Paulo,Human Genome and Stem Cell Center, Biosciences Institute
[5] University of São Paulo Medical School,Department of Neurology
关键词
Apolipoprotein E; Cognition; Dementia; Neuritic plaques; Neurofibrillary tangles; Mediation analysis;
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