Tropical cyclones (TCs) constitute one of the major atmospheric activities affecting the air quality of the Pearl River Delta region. In this study, the impact of TCs on air quality in Hong Kong during the TCactive season (July–October) from 2000 to 2015 is investigated. It is found that 57.5% of days with concentration of particulate matter with an aerodynamic diameter ≤ 10 µm (PM10) above the 90th percentile are related to TCactivity. TCs in three regions, located to the east, southeast, and southwest of Hong Kong, have obvious impacts on pollutant concentration. When TCs are located east of Hong Kong near Taiwan, 65.5%/38.7% of the days have high or extremely high PM10/ozone (O3) levels, which are associated with northerly wind, sinking motion, and relatively low precipitation. When TCs are located southeast of Hong Kong, 48.1%/58.2% of the days have high pollution levels, associated mainly with continental air mass transport. When TCs are south or west of Hong Kong, only 20.8%/16.9% of the days have high PM10/O3 levels, and the air quality in Hong Kong is generally good or normal due to TC-associated precipitation, oceanic air mass transport, and an enhanced rising motion. The higher chance of high O3 days when TCs are present between Hong Kong and Taiwan, possibly due to lower-than-normal precipitation along the east coast of China under TCcirculation. The results in this study highlight the important influence of TCposition and associated atmospheric circulations on the air quality in Hong Kong.