Low human beta-defensin-2 levels in the sputum of COPD patients are associated with the risk of exacerbations

被引：0
|
作者：
Shengchuan Feng
Yuqiong Yang
Fengyan Wang
Weijuan Shi
Jiaxuan Xu
Guoyan Tang
Jiaxing Xie
Nanshan Zhong
Zhenyu Liang
Rongchang Chen
机构：
[1] The First Affiliated Hospital of Guangzhou Medical University,Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine
[2] Shenzhen People’s Hospital (The Second Clinical Medical College,Department of Pulmonary and Critical Care Medicine, Shenzhen Institute of Respiratory Diseases
[3] Jinan University; The First Affiliated Hospital,undefined
[4] Southern University of Science and Technology),undefined
来源：
BMC Pulmonary Medicine | / 23卷
关键词：
Chronic obstructive pulmonary disease (COPD); hBD-2; Exacerbations; Microbial colonization; Cytokines;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Comparison of gingival crevicular fluid and serum human beta-defensin-2 levels between periodontal health and disease
    Ozturk, Ayla
    Kurt-Bayrakdar, Sevda
    Avci, Bahattin
    ORAL DISEASES, 2021, 27 (04) : 993 - 1000
  • [22] Serum Human Beta-Defensin-2 Is a Possible Biomarker for Monitoring Response to JAK Inhibitor in Psoriasis Patients
    Jin, Tingting
    Sun, Ziwen
    Chen, Xixue
    Wang, Yun
    Li, Ruoyu
    Ji, Suzhen
    Zhao, Yi
    DERMATOLOGY, 2017, 233 (2-3) : 164 - 169
  • [23] Gingival crevicular fluid levels of human beta-defensin-2 and cathelicidin in smoker and non-smoker patients: a cross-sectional study
    Ertugrul, A. S.
    Sahin, H.
    Dikilitas, A.
    Alpaslan, N. Z.
    Bozoglan, A.
    Tekin, Y.
    JOURNAL OF PERIODONTAL RESEARCH, 2014, 49 (03) : 282 - 289
  • [24] Immune regulatory functions of human beta-defensin-2 in odontoblast-like cells
    Dommisch, H.
    Winter, J.
    Willebrand, C.
    Eberhard, J.
    Jepsen, S.
    INTERNATIONAL ENDODONTIC JOURNAL, 2007, 40 (04) : 300 - 307
  • [25] Increased fecal human beta-defensin-2 expression in preterm infants is associated with allergic disease development in early childhood
    Hua, Man-Chin
    Chen, Chien-Chang
    Liao, Sui-Ling
    Yao, Tsung-Chieh
    Tsai, Ming-Han
    Lai, Shen-Hao
    Su, Kuan-Wen
    Chen, Li-Chen
    Chiu, Chih-Yung
    Yeh, Kuo-Wei
    Huang, Jing-Long
    WORLD ALLERGY ORGANIZATION JOURNAL, 2022, 15 (05):
  • [26] Fusion expression of human beta-defensin-2 from multiple joined genes in Escherichia coli
    Wang, F
    Fang, XM
    Xu, ZN
    Peng, L
    Ceni, PL
    PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, 2004, 34 (03): : 215 - 225
  • [27] Preferential codons enhancing the expression level of human beta-defensin-2 in recombinant Escherichia coli
    Peng, L
    Xu, ZN
    Fang, XM
    Wang, F
    Yang, S
    Cen, PL
    PROTEIN AND PEPTIDE LETTERS, 2004, 11 (04): : 339 - 344
  • [28] Alterations in sputum inflammatory markers during exacerbations for COPD patients with different stable state levels
    Haaland, Ingvild
    Tangedal, Solveig
    Nielsen, Rune
    Aanerud, Marianne
    Bakke, Per S.
    Eagan, Tomas M.
    EUROPEAN RESPIRATORY JOURNAL, 2019, 54
  • [29] NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2
    Voss, E
    Wehkamp, J
    Wehkamp, K
    Stange, EF
    Schröder, JM
    Harder, J
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (04) : 2005 - 2011
  • [30] Inhibitory effect of recombinant human beta-defensin-2 on angiogenesis and inflammatory factors of rat model of endometriosis
    Chen, Shuqin
    Jiang, Hongye
    Li, Jinbo
    Niu, Gang
    Yao, Shuzhong
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2017, 10 (05): : 7949 - 7956
12345