Melatonin and ulceration in rat stomach in acute emotional stress

被引：0
|
作者：
S. S. Pertsov
A. S. Sosnovskii
G. V. Pirogova
机构：
[1] Russian Academy of Medical Sciences,P. K. Anokhin Institute of Normal Physiology
来源：
Bulletin of Experimental Biology and Medicine | 1998年 / 125卷
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摘要：
Formation of peptic ulcers under conditions of acute emotional stress was studied in rats injected with different doses of melatonin (0.5, 1, and 2 mg/kg). The number of total length of peptic ulcers increases under conditions of stress. In unstressed rats melatonin induces ulceration of gastric mucosa. In a dose of 1 mg/kg melatonin exerts protective effect on gastric mucosa. No significant changes in the number and total length of peptic ulcers are noted with 0.5 and 2 mg/kg melatonin.
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页码：7 / 9
页数：2
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