Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance?

被引:0
|
作者
Michael Hölzel
Anton Bovier
Thomas Tüting
机构
[1] Michael Hlzel is at the Unit for RNA Biology,Department of Clinical Chemistry and Clinical Pharmacology
[2] University of Bonn,Department of Dermatology and Allergy
[3] 53105 Bonn,undefined
[4] Germany.,undefined
[5] Anton Bovier is at the Institute for Applied Mathematics,undefined
[6] University of Bonn,undefined
[7] 53115 Bonn,undefined
[8] Germany.,undefined
[9] Thomas Tüting is at the Laboratory of Experimental Dermatology,undefined
[10] University of Bonn,undefined
[11] 53105 Bonn,undefined
[12] Germany.,undefined
来源
Nature Reviews Cancer | 2013年 / 13卷
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摘要
Using malignant melanoma as a paradigm, these authors propose that therapy-induced injury to tumour tissue and the resultant inflammation can activate protective and regenerative responses that represent a shared resistance mechanism to different treatments.
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页码:365 / 376
页数:11
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