Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing

被引：0
|
作者：
Dirk Heckl
Monika S Kowalczyk
David Yudovich
Roger Belizaire
Rishi V Puram
Marie E McConkey
Anne Thielke
Jon C Aster
Aviv Regev
Benjamin L Ebert
机构：
[1] Brigham and Women's Hospital,Division of Hematology, Department of Medicine
[2] Harvard Medical School,Department of Pathology
[3] Broad Institute of MIT and Harvard,Department of Biology
[4] Brigham and Women's Hospital,undefined
[5] Harvard Medical School,undefined
[6] Howard Hughes Medical Institute,undefined
[7] Massachusetts Institute of Technology,undefined
[8] Current address: Institute of Experimental Hematology,undefined
[9] Hannover Medical School,undefined
[10] Hannover,undefined
[11] Germany.,undefined
来源：
Nature Biotechnology | 2014年 / 32卷
关键词：
D O I：
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中图分类号：
学科分类号：
摘要：
The genetic complexity of human leukemia is modeled using the CRISPR-Cas9 system in mice.
引用
收藏
页码：941 / 946
页数：5
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