Seeking a MCL-1 inhibitor

被引:0
|
作者
G Brumatti
P G Ekert
机构
[1] Walter and Eliza Hall Institute of Medical Research,Cell Signaling and Cell Death Division
[2] University of Melbourne,Department of Paediatrics
来源
关键词
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1440 / 1441
页数:1
相关论文
共 50 条
  • [21] A novel Mcl-1 inhibitor synergizes with venetoclax to induce apoptosis in cancer cells
    Zhao, Tianming
    He, Qiang
    Xie, Shurong
    Zhan, Huien
    Jiang, Cheng
    Lin, Shengbin
    Liu, Fangshu
    Wang, Cong
    Chen, Guo
    Zeng, Hui
    MOLECULAR MEDICINE, 2023, 29 (01)
  • [22] Mcl-1 Inhibitor enhances the proapoptotic effects of vemurafenib in melanoma cell lines
    Sarif, Z.
    Dogan, A.
    Eberle, J.
    EXPERIMENTAL DERMATOLOGY, 2023, 32 (04) : E108 - E108
  • [23] A novel selective Mcl-1 inhibitor exhibits in vitro and in vivo efficacy in melanoma
    Kump, Karson J.
    Miao, Lei
    Mady, Ahmed S.
    Lev, Katherine
    Giblin, William
    Skinner, Mary E.
    Lombard, David B.
    Nikolovska-Coleska, Zaneta
    CANCER RESEARCH, 2017, 77
  • [24] Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity
    Szlavik, Zoltan
    Ondi, Levente
    Csekei, Marton
    Paczal, Attila
    Szabo, Zoltan B.
    Radics, Gabor
    Murray, James
    Davidson, James
    Chen, Ijen
    Davis, Ben
    Hubbard, Roderick E.
    Pedder, Christopher
    Dokurno, Pawel
    Surgenor, Allan
    Smith, Julia
    Robertson, Alan
    LeToumelin-Braiza, Gaetane
    Cauqui, Nicolas
    Zarka, Marion
    Demarles, Didier
    Perron-Sierra, Francoise
    Claperon, Audrey
    Colland, Frederic
    Geneste, Olivier
    Kotschy, Andras
    JOURNAL OF MEDICINAL CHEMISTRY, 2019, 62 (15) : 6913 - 6924
  • [25] Preclinical evaluation of AMG 176, a novel, potent and selective Mcl-1 inhibitor with robust anti-tumor activity in Mcl-1 dependent cancer models
    Caenepeel, Sean R.
    Belmontes, Brian
    Sun, Jan
    Coxon, Angela
    Moody, Gordon
    Hughes, Paul E.
    CANCER RESEARCH, 2017, 77
  • [26] Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis
    Nencioni, A
    Hua, F
    Dillon, CP
    Yokoo, R
    Scheiermann, C
    Cardone, MH
    Barbieri, E
    Rocco, I
    Garuti, A
    Wesselborg, S
    Belka, C
    Brossart, P
    Patrone, F
    Ballestrero, A
    BLOOD, 2005, 105 (08) : 3255 - 3262
  • [27] A novel Mcl-1 inhibitor synergizes with venetoclax to induce apoptosis in cancer cells
    Tianming Zhao
    Qiang He
    Shurong Xie
    Huien Zhan
    Cheng Jiang
    Shengbin Lin
    Fangshu Liu
    Cong Wang
    Guo Chen
    Hui Zeng
    Molecular Medicine, 29
  • [28] Small molecule Mcl-1 inhibitor for triple negative breast cancer therapy
    Dong, Shengli
    Alahari, Suresh K.
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2024, 12
  • [29] Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies
    Tantawy, Shady I.
    Sarkar, Aloke
    Hubner, Stefan
    Tan, Zhi
    Wierda, William G.
    Eldeib, Abdelraouf
    Zhang, Shuxing
    Kornblau, Steven
    Gandhi, Varsha
    CLINICAL CANCER RESEARCH, 2023, 29 (02) : 446 - 457
  • [30] BRAF/MEK inhibitors selectively prime melanoma for Mcl-1 dependence and sensitize to Mcl-1 inhibition
    Kump, Karson J.
    Miao, Lei
    Ansari, Nurul
    Lombard, David B.
    Nikolovska-Coleska, Zaneta
    CANCER RESEARCH, 2019, 79 (13)