Use of ICAM-1 antibodies and antisense oligonucleotides to inhibit transmigration of neutrophils

被引：0
|
作者：
A. M. Sadowska
F. J. van Overveld
C. Luyten
P. Germonpré
W. A. De Backer
机构：
[1] University of Antwerp (UIA),Department of Respiratory Medicine, Antwerp Metabolic Research Unit
来源：
Inflammation Research | 2004年 / 53卷
关键词：
Antisense oligonucleotides; ICAM-1; neutrophil migration;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objective: The increase in adhesion molecule expression during the initial phase of inflammation leads to transmigration of neutrophils. Inhibition of this transmigration could decrease inflammatory response and tissue damage.
引用
收藏
页码：143 / 149
页数：6
相关论文
共 50 条
  • [41] Coordinated redistribution of leukocyte LFA-1 and endothelial cell ICAM-1 accompany neutrophil transmigration
    Shaw, SK
    Ma, S
    Kim, MB
    Rao, RM
    Hartman, CU
    Froio, RM
    Yang, L
    Jones, T
    Liu, Y
    Nusrat, A
    Parkos, CA
    Luscinskas, FW
    JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 200 (12): : 1571 - 1580
  • [42] Tissue-Specific ICAM-1 Expression and Neutrophil Transmigration in the Copper-Deficient Rat
    Dale A. Schuschke
    Susan S. Percival
    David Lominadze
    Jack T. Saari
    Alex B. Lentsch
    Inflammation, 2002, 26 : 297 - 303
  • [43] Tissue-specific ICAM-1 expression and neutrophil transmigration in the copper-deficient rat
    Schuschke, DA
    Percival, SS
    Lominadze, D
    Saari, JT
    Lentsch, AB
    INFLAMMATION, 2002, 26 (06) : 297 - 303
  • [44] Effects of ICAM-1 antisense oligonucleotide on the tubulointerstitium in mice with unilateral ureteral obstruction
    Cheng, QL
    Chen, XM
    Li, F
    Lin, HL
    Ye, YZ
    Fu, B
    KIDNEY INTERNATIONAL, 2000, 57 (01) : 183 - 190
  • [45] Effects of an antisense oligonucleotide inhibitor of human ICAM-1 on fetal development in rabbits
    Henry, SP
    Denny, KH
    Templin, MV
    Yu, RZ
    Levin, AA
    BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY, 2004, 71 (06) : 368 - 373
  • [46] The Role of Matrix Metalloproteinase-9 (MMP-9) and Intercellular Adhesion Molecule-1 (ICAM-1) in the Transmigration of Neutrophils in Intra-Amniotic Infection
    Hsu, Chaur-Dong
    Hong, Shihfen
    Hsu, Robert
    REPRODUCTIVE SCIENCES, 2009, 16 (03) : 202A - 202A
  • [47] OxLDL and substrate stiffness promote neutrophil transmigration by enhanced endothelial cell contractility and ICAM-1
    Stroka, Kimberly M.
    Levitan, Irena
    Aranda-Espinoza, Helim
    JOURNAL OF BIOMECHANICS, 2012, 45 (10) : 1828 - 1834
  • [48] Contrasting adhesion and functional responses to ICAM-1 by eosinophils and neutrophils in vitro.
    Bartemes, KR
    Iijima, K
    Kita, H
    FASEB JOURNAL, 2000, 14 (06): : A1141 - A1141
  • [49] Differential cardiopulmonary recruitment of neutrophils during hemorrhagic shock: A role for ICAM-1?
    Song, Y
    Ao, LH
    Calkins, CM
    Raeburn, CD
    Harken, AH
    Meng, XH
    SHOCK, 2001, 16 (06): : 444 - 448
  • [50] Analysis of the roles of ICAM-1 in neutrophil transmigration using a reconstituted mammalian cell expression model: Implication of ICAM-1 cytoplasmic domain and Rho-dependent signaling pathway
    Sans, E
    Delachanal, E
    Duperray, A
    JOURNAL OF IMMUNOLOGY, 2001, 166 (01): : 544 - 551
12345