Intermittent maltose feeding enhances paclitaxel production in suspension culture of Taxus chinensis cells

被引:0
|
作者
Hyung-Kyoon Choi
Sang-Ic Kim
Joo-Sun Son
Seung-Suh Hong
Hyun-Soo Lee
In-Sik Chung
Hyong-Joo Lee
机构
[1] Samyang Genex Biotech Research Institute,Department of Genetic Engineering
[2] Kyung Hee University,Department of Food Science and Technology, School of Agricultural Biotechnology
[3] Seoul National University,undefined
来源
Biotechnology Letters | 2000年 / 22卷
关键词
intermittent feeding; maltose; paclitaxel;
D O I
暂无
中图分类号
学科分类号
摘要
High paclitaxel production (26 mg l−1) was achieved through the intermittent feeding of 3, 1, and 2% (w/v) sucrose at days 0, 7, and 21, respectively, to a suspension culture of Taxus chinensis cells. Intermittent feedings of 1 and 2% (w/v) maltose at days 7 and 21, respectively, to the culture increased the paclitaxel production up to 67 mg l−1.
引用
收藏
页码:1793 / 1796
页数:3
相关论文
共 50 条
  • [21] Improved Production of Paclitaxel from Suspension Culture of Taxus chinensis var. mairei by in situ Extraction with Organic Solvents
    未作君
    元英进
    吴兆亮
    吴金川
    Chinese Journal of Chemical Engineering, 2003, (02) : 104 - 106
  • [22] Significant improvement of taxane production in suspension cultures of Taxus chinensis by sucrose feeding strategy
    Wang, HQ
    Yu, JT
    Zhong, JJ
    PROCESS BIOCHEMISTRY, 2000, 35 (05) : 479 - 483
  • [23] Paclitaxel production in suspension cell cultures of Taxus
    Ketchum, REB
    Gibson, DM
    PLANT CELL TISSUE AND ORGAN CULTURE, 1996, 46 (01) : 9 - 16
  • [24] Improved paclitaxel accumulation in cell suspension cultures of Taxus chinensis by brassinolide
    Zang, X
    Mei, XG
    Zhang, CH
    Lu, CT
    Ke, T
    BIOTECHNOLOGY LETTERS, 2001, 23 (13) : 1047 - 1049
  • [25] Improved paclitaxel accumulation in cell suspension cultures of Taxus chinensis by brassinolide
    Xin Zang
    Xing-Guo Mei
    Chang-He Zhang
    Cui-Tao Lu
    Tie Ke
    Biotechnology Letters, 2001, 23 : 1047 - 1049
  • [26] Paclitaxel production using co-culture of Taxus suspension cells and paclitaxel-producing endophytic fungi in a co-bioreactor
    Li, Yong-Cheng
    Tao, Wen-Yi
    Cheng, Long
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2009, 83 (02) : 233 - 239
  • [27] Paclitaxel production using co-culture of Taxus suspension cells and paclitaxel-producing endophytic fungi in a co-bioreactor
    Yong-Cheng Li
    Wen-Yi Tao
    Long Cheng
    Applied Microbiology and Biotechnology, 2009, 83 : 233 - 239
  • [28] Enhanced production of paclitaxel by semi-continuous batch process (SCBP) in suspension culture of Taxus chinensis (vol 29, pg 583, 2001)
    Choi, HK
    Yun, JH
    Kim, SI
    Son, JS
    Kim, HR
    Kim, JH
    Choi, HJ
    Hong, SS
    ENZYME AND MICROBIAL TECHNOLOGY, 2002, 31 (03) : 368 - 368
  • [29] Protoplast culture and paclitaxel production by Taxus yunnanensis
    Luo, JP
    Mu, Q
    Gu, YH
    PLANT CELL TISSUE AND ORGAN CULTURE, 1999, 59 (01) : 25 - 29
  • [30] Enhancement of taxane production in suspension cultures of Taxus chinensis with elicitation
    Dong, Hao-Di
    Zhong, Jian-Jiang
    Huadong Ligong Daxue Xuebao /Journal of East China University of Science and Technology, 2002, 28 (01):