Intermittent maltose feeding enhances paclitaxel production in suspension culture of Taxus chinensis cells

被引:0
|
作者
Hyung-Kyoon Choi
Sang-Ic Kim
Joo-Sun Son
Seung-Suh Hong
Hyun-Soo Lee
In-Sik Chung
Hyong-Joo Lee
机构
[1] Samyang Genex Biotech Research Institute,Department of Genetic Engineering
[2] Kyung Hee University,Department of Food Science and Technology, School of Agricultural Biotechnology
[3] Seoul National University,undefined
来源
Biotechnology Letters | 2000年 / 22卷
关键词
intermittent feeding; maltose; paclitaxel;
D O I
暂无
中图分类号
学科分类号
摘要
High paclitaxel production (26 mg l−1) was achieved through the intermittent feeding of 3, 1, and 2% (w/v) sucrose at days 0, 7, and 21, respectively, to a suspension culture of Taxus chinensis cells. Intermittent feedings of 1 and 2% (w/v) maltose at days 7 and 21, respectively, to the culture increased the paclitaxel production up to 67 mg l−1.
引用
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页码:1793 / 1796
页数:3
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