New Developments in Assessing Risk of Local Recurrence in Patients with Ductal Carcinoma In Situ after Lumpectomy and Breast Radiation

被引：0
|
作者：
Lalani N. [1 ,2 ]
Nofech-Mozes S. [1 ,4 ,5 ]
Rakovitch E. [1 ,2 ,3 ]
机构：
[1] University of Toronto, Toronto, ON
[2] Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, M4N 3M5, ON
[3] Institute for Clinical Evaluative Sciences (ICES), Toronto, ON
[4] Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, ON
[5] Department of Laboratory Medicine and Pathobiology, Toronto, ON
来源：
Current Breast Cancer Reports | 2016年 / 8卷 / 2期
关键词：
DCIS; Ductal carcinoma in situ; Predictive markers; Recurrence; Risk;
D O I：
10.1007/s12609-016-0211-x
中图分类号：
学科分类号：
摘要：
Ductal carcinoma in situ of the breast comprises nearly 25 % of all diagnoses of breast cancer. The current paradigm for management of DCIS consists of breast-conserving surgery followed by post-operative radiotherapy. The goal of the treatment of DCIS is to reduce the risk of local recurrence (and invasive local recurrence) to prevent the detrimental psychological impact of recurrence and minimize the need for additional treatment. A number of clinical, pathological, and molecular variables have been identified as predictive markers of recurrence and can be used to help risk stratify women with this diagnosis. We present here a review of current markers of recurrence, risk prediction tools, and future directions. © 2016, Springer Science+Business Media New York.
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页码：118 / 126
页数：8
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