Synthesis and properties of 3-amino-2-(2-benzimidazolyl)-δ2-pyrrolizidin-1-one

被引：0
|
作者：
Volovenko Yu.M. [1 ]
机构：
[1] Taras Shevchenko Kiev University
来源：
Chemistry of Heterocyclic Compounds | 1997年 / 33卷 / 7期
关键词：
Chloride; Organic Chemistry; Benzimidazole; Acid Chloride; Protective Group;
D O I：
10.1007/BF02253040
中图分类号：
学科分类号：
摘要：
2-Benzimidazotylacetonitrile is acetylated by the acid chloride derivative of N-trifluoroacetylproline to give N- and C-acyl derivatives. Removal of the trifluoroacetyl protective group in the C-acyl derivatives is accompanied by cyclization to give 3-amino-2-(2-benzimidazolyl)-Δ2-pyrrolizidin-1-one. Exhaustive acylation of this product gives a derivative of a new heterocyclic system, namely, pyrrolizino[3′,2′:5,6]-pyrimido[3,4-a] benzimidazole. ©1998 Plenum Publishing Corporation.
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页码：854 / 856
页数：2
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