Synthesis and properties of 3-amino-2-(2-benzimidazolyl)-δ2-pyrrolizidin-1-one

被引：0

作者：

Volovenko Yu.M. ^{[1
]}

机构：

[1] Taras Shevchenko Kiev University

来源：

Chemistry of Heterocyclic Compounds | 1997年 / 33卷 / 7期

关键词：

Chloride; Organic Chemistry; Benzimidazole; Acid Chloride; Protective Group;

D O I：

10.1007/BF02253040

中图分类号：

学科分类号：

摘要：

2-Benzimidazotylacetonitrile is acetylated by the acid chloride derivative of N-trifluoroacetylproline to give N- and C-acyl derivatives. Removal of the trifluoroacetyl protective group in the C-acyl derivatives is accompanied by cyclization to give 3-amino-2-(2-benzimidazolyl)-Δ2-pyrrolizidin-1-one. Exhaustive acylation of this product gives a derivative of a new heterocyclic system, namely, pyrrolizino[3′,2′:5,6]-pyrimido[3,4-a] benzimidazole. ©1998 Plenum Publishing Corporation.

引用

页码：854 / 856

页数：2

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