Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

被引：0

作者：

Da Jia

Renata Z. Jurkowska

Xing Zhang

Albert Jeltsch

Xiaodong Cheng

机构：

[1] Emory University School of Medicine,Department of Biochemistry

[2] 1510 Clifton Road,undefined

[3] Atlanta,undefined

[4] Georgia 30322,undefined

[5] USA,undefined

[6] Biochemistry Laboratory,undefined

[7] School of Engineering and Science,undefined

[8] Jacobs University Bremen,undefined

[9] Campus Ring 1,undefined

来源：

Nature | 2007年 / 449卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

A crystal structure of a complex between the DNA methyltransferase regulatory factor Dnmt3L and the catalytic domain of Dnmt3a leads to a model being proposed for the preferential methylation of DNA on maternally imprinted genes.

引用

页码：248 / 251

页数：3

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