Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

被引：0
|
作者：
Da Jia
Renata Z. Jurkowska
Xing Zhang
Albert Jeltsch
Xiaodong Cheng
机构：
[1] Emory University School of Medicine,Department of Biochemistry
[2] 1510 Clifton Road,undefined
[3] Atlanta,undefined
[4] Georgia 30322,undefined
[5] USA,undefined
[6] Biochemistry Laboratory,undefined
[7] School of Engineering and Science,undefined
[8] Jacobs University Bremen,undefined
[9] Campus Ring 1,undefined
来源：
Nature | 2007年 / 449卷
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摘要：
A crystal structure of a complex between the DNA methyltransferase regulatory factor Dnmt3L and the catalytic domain of Dnmt3a leads to a model being proposed for the preferential methylation of DNA on maternally imprinted genes.
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页码：248 / 251
页数：3
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