Cytotoxicity, apoptosis induction, and mitotic arrest by a novel podophyllotoxin glucoside, 4DPG, in tumor cells

被引：0
|
作者：
Yi-lin Qi
Fan Liao
Chang-qi Zhao
Yong-da Lin
Ming-xue Zuo
机构：
[1] College of Life Sciences,
[2] Beijing Normal University,undefined
[3] Key Laboratory for Molecular Biology and Gene Engineering Drugs of Beijing,undefined
来源：
Acta Pharmacologica Sinica | 2005年 / 26卷
关键词：
4-demethyl-picropodophyllotoxin 7′-O-β-D-glucopyranoside; podophyllotoxin; flow cytometry; microtubulin; apoptosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1000 / 1008
页数：8
相关论文
共 50 条
  • [31] Specific induction of apoptosis and cytotoxicity of recombinant mistletoe lectin (rML) in human tumor cells in vitro.
    Möckel, B
    Burger, AM
    Mengs, U
    Zinke, H
    Fiebig, HH
    Lentzen, H
    CLINICAL CANCER RESEARCH, 1999, 5 : 3785S - 3785S
  • [32] Cytotoxicity of trans-chalcone and licochalcone A against breast cancer cells is due to apoptosis induction and cell cycle arrest
    Buso Bortolotto, Luis Felipe
    Barbosa, Flavia Regina
    Silva, Gabriel
    Bitencourt, Tamires Aparecida
    Beleboni, Rene Oliveira
    Baek, Seung Joon
    Marins, Mozart
    Fachin, Ana Lucia
    BIOMEDICINE & PHARMACOTHERAPY, 2017, 85 : 425 - 433
  • [33] Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells
    Tang, Yangzhong
    Orth, James D.
    Xie, Tiao
    Mitchison, Timothy J.
    CANCER LETTERS, 2011, 310 (01) : 15 - 24
  • [34] CCL113, a novel sulfonamide, induces selective mitotic arrest and apoptosis in HeLa and HepG2 cells
    Yi, Ruirong
    Ohno, Yoshifumi
    Tian, Zheng
    Guo, Shuhan
    Chen, Weiwei
    Ma, Xue
    Win, Nan Nwe
    Li, Qisen
    Vahed, Majid
    Saito, Kengo
    Nakamoto, Shingo
    Suganami, Akiko
    Isegawa, Naohisa
    Yoshida, Keisuke
    Harada, Shinji
    Tamura, Yutaka
    Nishida, Atsushi
    Shirasawa, Hiroshi
    ONCOLOGY REPORTS, 2020, 44 (06) : 2770 - 2782
  • [35] Bacterial cytotoxicity and induction of apoptosis in promyelocytic (line HL-60) cells by novel organotellurium compounds
    Sailer, BL
    Prow, T
    Dickerson, S
    Watson, J
    Liles, N
    Patel, SJ
    Van Fleet-Stalder, V
    Chasteen, TG
    ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 1999, 18 (12) : 2926 - 2933
  • [36] Induction of efficient apoptosis and cell-cycle arrest in tumor cells by adenovirus-mediated p53 A4 mutant
    Maeda, A
    Nakamura, S
    Isono, M
    Osaki, M
    Ito, H
    Sato, K
    PATHOLOGY INTERNATIONAL, 2006, 56 (03) : 126 - 134
  • [37] Cytotoxicity of mistletoe extracts and mistletoe lectins towards tumor cells due to the induction of programmed cell death (apoptosis)
    Fischer, S
    Fiebig, HH
    Kabelitz, D
    Scheffler, A
    Janssen, O
    EUROPEAN JOURNAL OF CANCER, 1997, 33 : 78 - 78
  • [38] A Novel Eg5 Inhibitor (LY2523355) Causes Mitotic Arrest and Apoptosis in Cancer Cells and Shows Potent Antitumor Activity in Xenograft Tumor Models
    Ye, Xiang S.
    Fan, Li
    Van Horn, Robert D.
    Nakai, Ryuichiro
    Ohta, Yoshihisa
    Akinaga, Shiro
    Murakata, Chikara
    Yamashita, Yoshinori
    Yin, Tinggui
    Credille, Kelly M.
    Donoho, Gregory P.
    Merzoug, Farhana F.
    Li, Heng
    Aggarwal, Amit
    Blanchard, Kerry
    Westin, Eric H.
    MOLECULAR CANCER THERAPEUTICS, 2015, 14 (11) : 2463 - 2472
  • [39] Furan-2-carboxamide derivative, a novel microtubule stabilizing agent induces mitotic arrest and potentiates apoptosis in cancer cells
    Shwetha, B.
    Srinivasa, Sudhanva M.
    Jagadeesha, G. S.
    Thimmegowda, N. R.
    Hamse, Vivek K.
    Sridhar, B. T.
    Thimmaiah, K. N.
    Kumar, C. S. Ananda
    Rangappa, Shobith
    Rangappa, K. S.
    BIOORGANIC CHEMISTRY, 2021, 108
  • [40] NSC606985, a novel camptothecin analog, induces apoptosis and growth arrest in prostate tumor cells
    Tan, Chen
    Cai, Li-Qun
    Wu, Wendy
    Qiao, Yaming
    Imperato-McGinley, Julianne
    Chen, Guo-Qiang
    Zhu, Yuan-Shan
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2009, 63 (02) : 303 - 312
12345