Effect of Paclitaxel on Antitumor Activity of Cyclophosphamide: Study on Two Transplanted Tumors in Mice

被引：0
|
作者：
V. I. Kaledin
V. P. Nikolin
N. A. Popova
I. A. Pyshnaya
L. A. Bogdanova
T. S. Morozkova
机构：
[1] Institute of Cytology and Genetics,
[2] Siberian Division of the Russian Academy of Sciences,undefined
[3] Novosibirsk State University,undefined
[4] Institute of Chemical Biology and Basic Medicine,undefined
[5] Siberian Division of the Russian Academy of Sciences,undefined
[6] Institute of Molecular Pathology and Pathomorphology,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2015年 / 160卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Antitumor effect of paclitaxel used as the monotherapy or in combination with cyclophosphamide was studied on CBA/LacSto mice with transplanted LS and RLS tumors characterized by high (LS) and low (RLS) sensitivity to cyclophosphamide. The therapeutic effects of cyclophosphamide and paclitaxel were summed in animals with drug-resistant RLS tumor, while combined use of these drugs in LS tumor highly sensitive to the apoptogenic effect of cyclophosphamide was no more effective than cyclophosphamide alone.
引用
收藏
页码：81 / 83
页数：2
相关论文
共 50 条
  • [21] EFFECT OF EXTRACTS OF SPIROBOLUS BUNGII ON TRANSPLANTED TUMORS IN MICE
    姜廷良
    严述常
    王素芬
    冯桂文
    李兰芳
    武桂兰
    JournalofTraditionalChineseMedicine, 1981, (01) : 27 - 33
  • [22] THE EFFECT OF THIOPROLINE ON TRANSPLANTED TUMORS IN NUDE-MICE
    ARMAND, JP
    NEULAT, I
    MARTY, C
    DELSOL, G
    BIOMEDICINE EXPRESS, 1980, 33 (06): : 171 - 172
  • [23] EFFECT OF POPULATION DENSITY ON MORTALITY OF MICE WITH TRANSPLANTED TUMORS
    DECHAMBRE, RP
    GOSSE, C
    PRESSE MEDICALE, 1969, 77 (29): : 1057 - +
  • [24] EFFECT OF PARENTERAL HETEROLOGOUS ALBUMIN ON TRANSPLANTED TUMORS IN MICE
    GAZET, JC
    MCKIBBIN, B
    PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1964, 115 (03): : 740 - &
  • [25] CARBON TETRACHLORIDE-INDUCED INCREASE IN THE ANTITUMOR-ACTIVITY OF CYCLOPHOSPHAMIDE IN MICE - A PHARMACOKINETIC STUDY
    HARRIS, RN
    BASSECHES, PJ
    APPEL, PL
    DURSKI, AM
    POWIS, G
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1984, 12 (03) : 167 - 172
  • [26] INFLUENCE OF 1-(ALKYLAMINO)SILATRANES AND ISONIAZID ON THE ANTITUMOR-ACTIVITY OF CYCLOPHOSPHAMIDE IN MICE BEARING SA 180 TUMORS
    KOZLOWSKI, H
    RADECKI, A
    LUKASIAK, J
    HRABOWSKA, M
    EXPERIMENTAL PATHOLOGY, 1985, 28 (04): : 215 - 223
  • [27] Antitumor effect of thymoquinone combined with resveratrol on mice transplanted with breast cancer
    Alobaedi, Omar H.
    Talib, Wamidh H.
    Basheti, Iman A.
    ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2017, 10 (04) : 378 - 386
  • [28] Antitumor effect of thymoquinone combined with resveratrol on mice transplanted with breast cancer
    Omar H.Alobaedi
    Wamidh H.Talib
    Iman A.Basheti
    Asian Pacific Journal of Tropical Medicine, 2017, (04) : 378 - 386
  • [29] ANTITUMOR-ACTIVITY OF MURINE TUMOR NECROSIS FACTOR (TNF) AGAINST TRANSPLANTED MURINE TUMORS AND HETEROTRANSPLANTED HUMAN-TUMORS IN NUDE-MICE
    HARANAKA, K
    SATOMI, N
    SAKURAI, A
    INTERNATIONAL JOURNAL OF CANCER, 1984, 34 (02) : 263 - 267
  • [30] Combined antitumor effect of cyclophosphamide and bromodeoxyuridine in BDF1 mice bearing L1210 ascites tumors
    Kagawa, Yoshiyuki
    Noge, Ichiro
    Higashigawa, Masamune
    Komada, Yoshihiro
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2008, 31 (01) : 57 - 61
12345