Extracellular Matrix in the Regulation of Stem Cell Differentiation

被引：0
|
作者：
E. S. Novoseletskaya
O. A. Grigorieva
A. Yu. Efimenko
N. I. Kalinina
机构：
[1] Lomonosov Moscow State University,Institute for Regenerative Medicine, Medical Research and Education Center
[2] Faculty of Medicine,Lomonosov Moscow State University
来源：
Biochemistry (Moscow) | 2019年 / 84卷
关键词：
extracellular matrix; stem cells; differentiation; stem cell niche; extracellular vesicles; decellularization;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Extracellular matrix (ECM) proteins fill the space between cells in multicellular organisms, contributing to the structure of organs and tissues. The mechanical properties of ECM are well studied. At present, the role of individual ECM components and the three-dimensional tissue-specific matrices in the regulation of cell functional activity, proliferation, migration, acquisition of a specialized phenotype and its maintenance is intensively studied. In this review, we described main ECM structural proteins, enzymes, and extracellular vesicles and present the data on the participation of ECM components in the regulation of stem cell differentiation and self-maintenance, as well as approaches to the modeling of stem cells microenvironment using decellularized ECM.
引用
收藏
页码：232 / 240
页数：8
相关论文
共 50 条
  • [21] Extracellular Matrix Proteins are Necessary for Mouse Embryonic Stem Cell Differentiation and May Guide Stem Cell Fate
    Taylor-Weiner, Hermes
    Engler, Adam J.
    BIOPHYSICAL JOURNAL, 2012, 102 (03) : 719A - 719A
  • [22] Regulation of the adult muscle stem cell niche by Notch and extracellular matrix signalling
    Baghdadi, Meryem
    Castel, David
    Fukada, So-ichiro
    Birk, David
    Relaix, Frederic
    Mourikis, Philippos
    Tajbakhsh, Shahragim
    MECHANISMS OF DEVELOPMENT, 2017, 145 : S173 - S173
  • [23] Regulation of Hematopoietic Stem Cell Behavior by the Nanostructured Presentation of Extracellular Matrix Components
    Muth, Christine Anna
    Steinl, Carolin
    Klein, Gerd
    Lee-Thedieck, Cornelia
    PLOS ONE, 2013, 8 (02):
  • [24] Regulation of the osteoblastic and chondrocytic differentiation of stem cells by the extracellular matrix and subsequent bone formation modes
    He, Jing
    Jiang, Bo
    Dai, Yun
    Hao, Jianyuan
    Zhou, Zongke
    Tian, Zhili
    Wu, Fang
    Gu, Zhongwei
    BIOMATERIALS, 2013, 34 (28) : 6580 - 6588
  • [25] CHARACTERIZING THE CONTRIBUTION OF EXTRACELLULAR MATRIX (ECM) TO MOUSE TROPHOBLAST STEM AND PROGENITOR CELL DIFFERENTIATION
    Harihara, Anirudha
    Gustin, Katarina
    Breen, Kellie
    Natale, Bryony
    Natale, David
    PLACENTA, 2016, 45 : 127 - 127
  • [26] Evaluating the effect of extracellular matrix (ECM) on mouse trophoblast stem and progenitor cell differentiation
    Harihara, A.
    Gustin, K.
    Natale, B. V.
    Natale, D. R.
    MOLECULAR BIOLOGY OF THE CELL, 2015, 26
  • [27] Vascular extracellular matrix and aortic cell differentiation
    Mecham, Robert
    FASEB JOURNAL, 2013, 27
  • [28] Induction of mesenchymal stem cell differentiation - early changes in cell-substrate/-extracellular matrix interactions
    Angstmann, M.
    Graf, F.
    Maercker, C.
    Breitkreutz, D.
    EUROPEAN JOURNAL OF CELL BIOLOGY, 2009, 88 : 39 - 39
  • [29] REGULATION OF EXTRACELLULAR-MATRIX DEGRADATION BY CELL EXTRACELLULAR-MATRIX INTERACTIONS
    WERB, Z
    TREMBLE, P
    DAMSKY, CH
    CELL DIFFERENTIATION AND DEVELOPMENT, 1990, 32 (03): : 299 - 306
  • [30] Regulation of human mesenchymal stem cells differentiation into chondrocytes in extracellular matrix-based hydrogel scaffolds
    Du, Mingchun
    Liang, Hui
    Mou, Chenchen
    Li, Xiaoran
    Sun, Jie
    Zhuang, Yan
    Xiao, Zhifeng
    Chen, Bing
    Dai, Jianwu
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2014, 114 : 316 - 323
12345