Understanding the pathophysiology of hemodialysis access problems as a prelude to developing innovative therapies

被引：0
|
作者：
Charles J Diskin
Thomas J Stokes
Linda M Dansby
Lautrec Radcliff
Thomas B Carter
机构：
[1] CJ Diskin is a Clinical Associate Professor,
[2] TJ Stokes is a Clinical Associate Professor,undefined
[3] and LM Dansby,undefined
[4] L Radcliff and TB Carter are Nephrologists in the Hypertension,undefined
[5] Nephrology,undefined
[6] Dialysis and Transplantation Clinic,undefined
[7] Auburn University,undefined
[8] Opelika,undefined
[9] AL,undefined
[10] USA.,undefined
来源：
Nature Clinical Practice Nephrology | 2008年 / 4卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Maintenance of a functioning vascular access for hemodialysis is a major challenge. This Review summarizes recent insights into the pathophysiology of the major complications of vascular accesses—thrombosis, stenosis, aneurysms, fistula maturation failure and catheter infection—and outlines innovative ideas for the prevention and treatment of these complications that have emerged as a result of our improved understanding. These ideas include interfering with bacterial quorum sensing, blocking growth factors that are involved in intimal hyperplasia, and inhibiting matrix metalloproteinases.
引用
收藏
页码：628 / 638
页数：10
相关论文
共 50 条
  • [31] UNDERSTANDING AND DEVELOPING INNOVATIVE PRODUCTS AND SERVICES: THE ESSENTIAL ELEMENTS
    Tan, A. R.
    McAloone, T. C.
    9TH INTERNATIONAL DESIGN CONFERENCE - DESIGN 2006, VOLS 1 AND 2, 2006, (36): : 647 - +
  • [32] Vascular access for hemodialysis: will the tunnelled atrial cathetersolve the problems?
    Ritz, E
    Zeier, M
    DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2004, 129 (47) : 2527 - 2528
  • [33] Hemodialysis: Management problems in developing countries, with Nigeria as a surrogate
    Bamgboye, EL
    KIDNEY INTERNATIONAL, 2003, 63 : 93 - 95
  • [34] PAYING FOR CURES: AN ANALYSIS OF INNOVATIVE ACCESS AGREEMENTS FOR LICENSED GENE THERAPIES
    Hogg, L.
    Richards, M.
    VALUE IN HEALTH, 2019, 22 : S431 - S431
  • [35] DRUG ACCESS REQUESTS FOR INNOVATIVE THERAPIES FOR PEDIATRIC ONCOLOGY PATIENTS IN CANADA
    Judd, Sandra
    Revon-Riviere, Gabriel
    Deyell, Rebecca J.
    Vanan, Magimairajan Issai
    Pecheux, Lucie
    Zorzi, Alexandra P.
    Santiago, Raoul
    Tran, Thai Hoa
    Grover, Stephanie A.
    Cohen-Gogo, Sarah
    Morgenstern, Daniel
    PEDIATRIC BLOOD & CANCER, 2022, 69 : S317 - S318
  • [36] Access to innovative therapies in pediatric oncology: Report of the nationwide experience in Canada
    Judd, Sandra
    Revon-Riviere, Gabriel
    Grover, Stephanie A.
    Deyell, Rebecca J.
    Vanan, Magimairajan Issai
    Lewis, Victor A.
    Pecheux, Lucie
    Zorzi, Alexandra P.
    Goudie, Catherine
    Santiago, Raoul
    Tran, Thai Hoa
    Abbott, Lesleigh S.
    Brossard, Josee
    Moorehead, Paul
    Alvi, Saima
    Portwine, Carol
    Denburg, Avram
    Whitlock, James A.
    Cohen-Gogo, Sarah
    Morgenstern, Daniel A.
    CANCER MEDICINE, 2024, 13 (03):
  • [37] Exploring the boundaries of autonomy and the ‘right’ to access innovative stem cell therapies
    Lysaght T.
    Richards B.
    Muralidharan A.
    Asian Bioethics Review, 2017, 9 (1-2) : 45 - 60
  • [38] Understanding the Pathophysiology of Ischemic Stroke: The Basis of Current Therapies and Opportunity for New Ones
    Salaudeen, Maryam A.
    Bello, Nura
    Danraka, Rabiu N.
    Ammani, Maryam L.
    BIOMOLECULES, 2024, 14 (03)
  • [39] Improved understanding of the pathophysiology of sepsis: Setting the scene for potential novel adjunctive therapies
    Chausse, J. M.
    Malekele, L.
    Paruk, F.
    SOUTHERN AFRICAN JOURNAL OF CRITICAL CARE, 2018, 34 (01) : 4 - 8
  • [40] Understanding Surgical Preference and Practice in Hemodialysis Vascular Access Creation
    Nica, Andra
    Lok, Charmaine E.
    Harris, Jeremy
    Lee, Timmy C.
    Mokrzycki, Michele H.
    Maya, Ivan D.
    Vazquez, Miguel A.
    Xi, Wang
    Moist, Louise M.
    SEMINARS IN DIALYSIS, 2013, 26 (04) : 520 - 526
12345