Envelope 2 protein phosphorylation sites S75 & 277 of hepatitis C virus genotype 1a and interferon resistance: A sequence alignment approach

被引:0
|
作者
Samia Afzal
Muhammad Idrees
Muhammad Ali
Muhammad Ilyas
Abrar Hussain
Madiha Akram
Sadia Butt
Sana Saleem
Irshadur Rehman
Liaqat Ali
Muhammad Shahid
机构
[1] National Centre of Excellence in Molecular Biology,
[2] University of the Punjab,undefined
来源
关键词
Interferon Resistance; CLK2 Kinase;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 29 条
  • [21] The updated chemiluminescence enzyme immunoassay as a tool for monitoring hepatitis C virus core protein during interferon alpha-2b and ribavirin therapy in patients with genotype 1 and high viral loads.
    Enomoto, M
    Kohmoto, M
    Tanaka, M
    Tamori, A
    Habu, D
    Takeda, T
    Seki, S
    Shiomi, S
    Nishiguchi, S
    HEPATOLOGY, 2004, 40 (04) : 688A - 688A
  • [22] A Recombinant Hepatitis C Virus Genotype 1a E1/E2 Envelope Glycoprotein Vaccine Elicits Antibodies That Differentially Neutralize Closely Related 2a Strains through Interactions of the N-Terminal Hypervariable Region 1 of E2 with Scavenger Receptor B1
    Johnson, Janelle
    Freedman, Holly
    Logan, Michael
    Wong, Jason Alexander Ji-Xhin
    Hockman, Darren
    Chen, Chao
    He, Jianqi
    Beard, Michael R.
    Eyre, Nicholas S.
    Baumert, Thomas F.
    Tyrrell, D. Lorne
    Law, John L. M.
    Houghton, Michael
    JOURNAL OF VIROLOGY, 2019, 93 (22)
  • [23] Baseline Polymorphisms and Emergence of Drug Resistance in the NS3/4A Protease of Hepatitis C Virus Genotype 1 following Treatment with Faldaprevir and Pegylated Interferon Alpha 2a/Ribavirin in Phase 2 and Phase 3 Studies
    Berger, K. L.
    Scherer, J.
    Ranga, M.
    Sha, N.
    Stern, J. O.
    Quinson, A. -M.
    Kukolj, G.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2015, 59 (10) : 6017 - 6025
  • [24] Prevalence of hepatitis C virus genotype 1a in Japan and correlation of mutations in the NS5A region and single-nucleotide polymorphism of interleukin-28B with the response to combination therapy with pegylated-interferon-alpha 2b and ribavirin
    Hayashi, Kazuhiko
    Katano, Yoshiaki
    Kuzuya, Teiji
    Tachi, Yoshihiko
    Honda, Takashi
    Ishigami, Masatoshi
    Itoh, Akihiro
    Hirooka, Yoshiki
    Ishikawa, Tetsuya
    Nakano, Isao
    Urano, Fumihiro
    Yoshioka, Kentaro
    Toyoda, Hidenori
    Kumada, Takashi
    Goto, Hidemi
    JOURNAL OF MEDICAL VIROLOGY, 2012, 84 (03) : 438 - 444
  • [25] Analysis of the PKR-eIF2alpha phosphorylation homology domain (PePHD) of hepatitis C virus genotype 1 in HIV-coinfected patients by ultra-deep pyrosequencing and its relationship to responses to pegylated interferon-ribavirin treatment
    Bolcic, F.
    Sede, M.
    Moretti, F.
    Westergaard, G.
    Vazquez, M.
    Laufer, N.
    Quarleri, J.
    ARCHIVES OF VIROLOGY, 2012, 157 (04) : 703 - 711
  • [26] Analysis of the PKR-eIF2alpha phosphorylation homology domain (PePHD) of hepatitis C virus genotype 1 in HIV-coinfected patients by ultra-deep pyrosequencing and its relationship to responses to pegylated interferon-ribavirin treatment
    F. Bolcic
    M. Sede
    F. Moretti
    G. Westergaard
    M. Vazquez
    N. Laufer
    J. Quarleri
    Archives of Virology, 2012, 157 : 703 - 711
  • [27] Prevalence of resistance mutations against NS3 protease inhibitors in patients with hepatitis C virus genotype 1b and response to telaprevir plus pegylated-interferon-alpha 2b and ribavirin combination therapy
    Hayashi, Kazuhiko
    Katano, Yoshiaki
    Honda, Takashi
    Kuzuya, Teiji
    Ishizu, Yoji
    Ishigami, Masatoshi
    Goto, Hidemi
    HEPATOLOGY, 2013, 58 : 1151A - 1151A
  • [28] Drug Resistance Mutations in the Ns3 and NS5A Regions in Patients With Hepatitis C Virus Genotype 1b and Response to Telaprevir Plus Pegylated-Interferon-Alpha 2B and Ribavirin Combination Therapy
    Hayashi, Kazuhiko
    Ishigami, Masatoshi
    Ishizu, Yoji
    Kuzuya, Teiji
    Honda, Takashi
    Katano, Yoshiaki
    Hirooka, Yoshiki
    Goto, Hidemi
    GASTROENTEROLOGY, 2014, 146 (05) : S979 - S979
  • [29] Pretreatment levels of interferon-gamma inducible protein 10 kda (IP-10) predict viral kinetic response and outcome in difficult-to-treat patients with chronic hepatitis C virus genotype 1 infection receiving peginterferon alfa-2a and ribavirin
    Lagging, M
    Romero, A
    Westin, J
    Pawlotsky, JM
    Zeuzem, S
    Negro, F
    Schalm, SW
    Haagmans, BL
    Ferrari, C
    Neumann, AU
    Hellstrand, K
    HEPATOLOGY, 2005, 42 (04) : 649A - 649A