A New Diarylheptanoid Bearing the Flavonol Moiety from Alpinia officinarum and its Xanthine Oxidase Inhibitory Activity

被引:0
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作者
Shu Hui Wu
Yao Xin Zhao
Jie Zhou
Guo Fei Ma
Ling Zhao
机构
[1] Wuhan Polytechnic University,School of Biology and Pharmaceutical Engineering
[2] Hubei Province Key Laboratory of Conservation Biology for Shennongjia Golden Monkey,undefined
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关键词
diarylheptanoid; officinine C; xanthine oxidase;
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摘要
A novel diarylheptanoid-flavonol dimer (1), named officinin C, was isolated from the rhizomes of Alpinia officinarum Hance. The structure elucidation was accomplished by HR-ESI-MS and 1D and 2D NMR methods. Its xanthine oxidase inhibitory activity was tested along with officinin A (2). At the concentration of 25 μM, compounds 1 and 2 can reach 57 and 52% inhibition rates against xanthine oxidase.
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页码:26 / 29
页数:3
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