Hypercohones A–C, acylphloroglucinol derivatives with homo-adamantane cores from Hypericum cohaerens

被引:23
|
作者
Liu X. [1 ,2 ]
Yang X.-W. [1 ,2 ]
Chen C.-Q. [1 ]
Wu C.-Y. [1 ]
Zhang J.-J. [1 ,2 ]
Ma J.-Z. [1 ]
Wang H. [1 ]
Zhao Q.-S. [1 ]
Yang L.-X. [1 ]
Xu G. [1 ]
机构
[1] State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming
[2] University of Chinese Academy of Sciences, Beijing
关键词
acylphloroglucinol; adamantane; hypercohone; Hypericum cohaerens;
D O I
10.1007/s13659-013-0032-9
中图分类号
学科分类号
摘要
Three new homo-adamantanyl type natural products were derived from polyprenylated polycyclic acylphloroglucinol. Hypercohones A-C (1–3), along with five other known hypercohones (4–8), were isolated from the aerial parts of Hypericum cohaerens. The structures of 1–3 were elucidated on the basis of comprehensive spectroscopic analysis. The inhibitory activities of these isolates against five human cancer cell lines in vitro were tested. [Figure not available: see fulltext.]. © 2013, The Author(s).
引用
收藏
页码:233 / 237
页数:4
相关论文
共 47 条
  • [41] Hyperacmosins H-J, three new polycyclic polyprenylated acylphloroglucinol derivatives from Hypericum acmosepalum (vol 17, pg 312, 2020)
    Wang, Xue
    Wang, Jia-Jia
    Suo, Xin-Yue
    Sun, Hao-Ran
    Zhen, Bo
    Sun, Hua
    Li, Jian-Guang
    Ji, Teng-Fei
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2020, 22 (10) : 995 - 997
  • [42] Hyperpatulols A-I, spirocyclic acylphloroglucinol derivatives with anti-migration activities from the flowers of hypericum patulum (vol 87, pg 409, 2019)
    Liu, Yang-Yang
    Ao, Zhen
    Xu, Qi-Qi
    Zhu, Dong-Rong
    Chen, Chen
    Wang, Xiao-Bing
    Luo, Jian-Guang
    Kong, Ling-Yi
    BIOORGANIC CHEMISTRY, 2020, 104
  • [43] Petiolins A-C, phloroglucinol derivatives from Hypericum pseudopetiolatum var. kiusianum
    Tanaka, Naonobu
    Kubota, Takaaki
    Ishiyama, Haruaki
    Araki, Atsushi
    Kashiwada, Yoshiki
    Takaishi, Yoshihisa
    Mikami, Yuzuru
    Kobayashi, Jun'ichi
    BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (10) : 5619 - 5623
  • [44] MOLECULAR-MOTION AND METHYL-GROUP ROTATION BARRIERS FROM C-13 NMR RELAXATION-TIMES, NORBORNANE AND ADAMANTANE DERIVATIVES IN SOLUTION
    BEIERBECK, H
    MARTINO, R
    SAUNDERS, JK
    CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1980, 58 (02): : 102 - 109
  • [45] SYNTHESIS OF ADAMANTANE DERIVATIVES .42. NOVEL SYNTHESIS OF 5-METHYLENE-4-AZAHOMOADAMANTANE DERIVATIVES FROM 2-METHYL-2-HYDROXYADAMANTANE AND THEIR C-13 NUCLEAR MAGNETIC-RESONANCE SPECTRA
    SASAKI, T
    EGUCHI, S
    TOI, N
    JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (20): : 3810 - 3813
  • [46] Sampsoniones C-H, a unique family of polyprenylated benzophenone derivatives with the novel tetracyclo[7.3.1.13,11.03,7]tetradecane-2,12,14-trione skeleton, from Hypericum sampsonii (Guttiferae)
    Hu, LH
    Sim, KY
    TETRAHEDRON LETTERS, 1999, 40 (04) : 759 - 762
  • [47] 2-Substituted and 2,2-disubstituted adamantane derivatives as models for studying substituent chemical shifts and C-Hax•••Yax cyclohexane contacts-results from experimental and theoretical NMR spectroscopic chemical shifts and DFT structures
    Kolocouris, Antonios
    Koch, Andreas
    Kleinpeter, Erich
    Stylianakis, Ioannis
    TETRAHEDRON, 2015, 71 (16) : 2463 - 2481