Hypercohones A–C, acylphloroglucinol derivatives with homo-adamantane cores from Hypericum cohaerens

被引:23
|
作者
Liu X. [1 ,2 ]
Yang X.-W. [1 ,2 ]
Chen C.-Q. [1 ]
Wu C.-Y. [1 ]
Zhang J.-J. [1 ,2 ]
Ma J.-Z. [1 ]
Wang H. [1 ]
Zhao Q.-S. [1 ]
Yang L.-X. [1 ]
Xu G. [1 ]
机构
[1] State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming
[2] University of Chinese Academy of Sciences, Beijing
关键词
acylphloroglucinol; adamantane; hypercohone; Hypericum cohaerens;
D O I
10.1007/s13659-013-0032-9
中图分类号
学科分类号
摘要
Three new homo-adamantanyl type natural products were derived from polyprenylated polycyclic acylphloroglucinol. Hypercohones A-C (1–3), along with five other known hypercohones (4–8), were isolated from the aerial parts of Hypericum cohaerens. The structures of 1–3 were elucidated on the basis of comprehensive spectroscopic analysis. The inhibitory activities of these isolates against five human cancer cell lines in vitro were tested. [Figure not available: see fulltext.]. © 2013, The Author(s).
引用
收藏
页码:233 / 237
页数:4
相关论文
共 47 条
  • [1] Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens
    Liu, Xia
    Yang, Xing-Wei
    Chen, Chao-Qun
    Wu, Chun-Yan
    Zhang, Jing-Jing
    Ma, Jun-Zeng
    Wang, Huan
    Yang, Li-Xin
    Xu, Gang
    JOURNAL OF NATURAL PRODUCTS, 2013, 76 (09): : 1612 - 1618
  • [2] homo-adamantane type polyprenylated acylphloroglucinols from Hypericum pseudohenryi
    Yang, Xing-Wei
    Wang, Huan
    Ma, Wei-Guang
    Xia, Fan
    Xu, Gang
    TETRAHEDRON, 2017, 73 (05) : 566 - 570
  • [3] Hypercohones D–G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens
    Zhang J.-J.
    Yang X.-W.
    Ma J.-Z.
    Liu X.
    Yang L.-X.
    Yang S.-C.
    Xu G.
    Natural Products and Bioprospecting, 2014, 4 (2) : 73 - 79
  • [4] homo-Adamantane type polycyclic polyprenylated acylphloroglucinols from Hypericum hookerianum
    Ye, Ye
    Yang, Xing-Wei
    Zhou, Yan
    Xu, Gang
    FITOTERAPIA, 2019, 133 : 43 - 50
  • [5] Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens (vol 76, pg 1612, 2013)
    Liu, Xia
    Yang, Xing-Wei
    Chen, Chao-Qun
    Wu, Chun-Yon
    Zhang, Jing-Jing
    Ma, Jun-Zeng
    Wang, Huan
    Yang, Li-Xin
    Xu, Gang
    JOURNAL OF NATURAL PRODUCTS, 2016, 79 (04): : 1223 - 1223
  • [6] Acylphloroglucinol derivatives from Hypericum prolificum
    Henry, Geneive E.
    Raithore, Smita
    Zhang, Yanjun
    Jayaprakasam, Bolleddula
    Nair, Muraleedharan G.
    Heber, David
    Seeram, Navindra P.
    JOURNAL OF NATURAL PRODUCTS, 2006, 69 (11): : 1645 - 1648
  • [7] Hyperuralones A and B, New Acylphloroglucinol Derivatives with Intricately Caged Cores from Hypericum uralum
    Zhang, Jing-Jing
    Yang, Jing
    Liao, Yang
    Yang, Xing-Wei
    Ma, Jun-Zeng
    Xiao, Qiu-Li
    Yang, Li-Xin
    Xu, Gang
    ORGANIC LETTERS, 2014, 16 (18) : 4912 - 4915
  • [8] Spirocyclic Acylphloroglucinol Derivatives from Hypericum pyramidatum
    Force, Rebecca
    Chen, Shui Ling
    Fortier, Emily
    Rowlands, Emily
    Heneks, Jean
    Rovnyak, David
    Henry, Geneive E.
    NATURAL PRODUCT COMMUNICATIONS, 2014, 9 (07) : 961 - 964
  • [9] New acylphloroglucinol derivatives from Hypericum prolificum
    Raithore, Smita
    Henry, Geneive E.
    Zhang, Yanjun
    Seeram, Navindra P.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [10] Spirocyclic Acylphloroglucinol Derivatives from Hypericum beanii
    Chen, Xuan-Qin
    Li, Yan
    Li, Kun-Zhi
    Peng, Li-Yan
    He, Juan
    Wang, Kou
    Pan, Zheng-Hong
    Cheng, Xiao
    Li, Ming-Ming
    Zhao, Qin-Shi
    Xu, Gang
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2011, 59 (10) : 1250 - 1253