Controlled S-nitrosation

被引：0
|
作者：
Steven R Tannenbaum
Ji-Eun Kim
机构：
[1] Division of Biological Engineering and Department of Chemistry,Division of Biological Engineering
[2] Massachusetts Institute of Technology,undefined
来源：
Nature Chemical Biology | 2005年 / 1卷
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学科分类号：
摘要：
Protein nitrosation is an important signaling mechanism in vivo; however, mechanisms for selective nitric oxide modification of cysteines have not been described. Thioredoxin is now shown to rapidly and site-specifically catalyze S-nitrosation of an active site cysteine of caspase-3.
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页码：126 / 127
页数：1
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