Changes in the Activity of Proteasomes and Calpains in Metastases of Human Lung Cancer and Breast Cancer

被引：0
|
作者：
E. E. Shashova
E. S. Kolegova
A. A. Zav’yalov
E. M. Slonimskaya
I. V. Kondakova
机构：
[1] Russian Academy of Sciences,Tomsk National Research Medical Center
来源：
Bulletin of Experimental Biology and Medicine | 2017年 / 163卷
关键词：
breast cancer; lung cancer; metastasis; chymotrypsin-related and caspase-like activity of proteasome; total activity of calpains;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In patients with breast cancer and lung cancer, chymotrypsin-like and caspase-like activities of proteasomes and total activity of calpains in the primary tumor nodes and lymphogenic metastasis are elevated in comparison with the corresponding normal tissues. The development of lymphogenic metastases of breast cancer and lung cancer was associated with opposite change in caspase-like activity of proteasomes. These results can be useful for the development of methods for evaluation of aggressiveness of breast and lung cancer.
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页码：486 / 489
页数：3
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