Tcf1 and Lef1 pack their own HDAC

被引:0
|
作者
Charles P Ng
Dan R Littman
机构
[1] Charles P. Ng is with The Kimmel Center for Biology and Medicine of the Skirball Institute,
[2] New York University School of Medicine,undefined
[3] New York,undefined
[4] New York,undefined
[5] USA.,undefined
[6] Dan R. Littman is with The Kimmel Center for Biology and Medicine of the Skirball Institute and the Howard Hughes Medical Institute,undefined
[7] New York University School of Medicine,undefined
[8] New York,undefined
[9] New York,undefined
[10] USA.,undefined
来源
Nature Immunology | 2016年 / 17卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The transcription factors Tcf1 and Lef1 have intrinsic histone-deacetylase activity that is required for the repression of CD4+ T cell–lineage genes in CD8+ T cells.
引用
收藏
页码:615 / 616
页数:1
相关论文
共 50 条
  • [41] TCF1 in T cell immunity: a broadened frontier
    Xudong Zhao
    Qiang Shan
    Hai-Hui Xue
    Nature Reviews Immunology, 2022, 22 : 147 - 157
  • [42] The Role of LEF1 in Endometrial Gland Formation and Carcinogenesis
    Shelton, Dawne N.
    Fornalik, Hubert
    Neff, Traci
    Park, Soo Yeun
    Bender, David
    DeGeest, Koen
    Liu, Xiaoming
    Xie, Weiliang
    Meyerholz, David K.
    Engelhardt, John F.
    Goodheart, Michael J.
    PLOS ONE, 2012, 7 (07):
  • [43] Regulation of the LEF1 gene's alternative promoter
    Pate, Kira T.
    Yokoyama, Noriko N.
    Waterman, Marian L.
    FASEB JOURNAL, 2010, 24
  • [44] Increased Lef1 Expression in Metastatic Prostate Cancer
    Huang, H.
    Li, Y.
    Melamed, J.
    Lee, P.
    de las Morenas, A.
    LABORATORY INVESTIGATION, 2009, 89 : 173A - 173A
  • [45] The nuclear interactions of the VDR and lef1 are ligand independent
    Luisella, C.
    Demay, M. B.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2007, 22 : S398 - S398
  • [46] Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas
    A. Bleckmann
    L. Siam
    F. Klemm
    E. Rietkötter
    Chr. Wegner
    F. Kramer
    T. Beissbarth
    C. Binder
    Chr. Stadelmann
    T. Pukrop
    Clinical & Experimental Metastasis, 2013, 30 : 471 - 482
  • [47] LEF1 Immunohistochemistry Identifies CTNNB1-mutated Medulloblastomas
    Thomas, Diana
    Murdoch, Geoffrey
    Hamilton, Ronald
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2017, 76 (06): : 541 - 542
  • [48] LEF1 isoforms regulate cellular senescence and aging
    Jia, Minxue
    Sayed, Khaled
    Kapetanaki, Maria G.
    Dion, William
    Rosas, Lorena
    Irfan, Saad
    Valenzi, Eleanor
    Mora, Ana L.
    Lafyatis, Robert A.
    Rojas, Mauricio
    Zhu, Bokai
    Benos, Panayiotis V.
    AGING CELL, 2023, 22 (12)
  • [49] LEF1 Expression in Genetically Defined Medulloblastoma Subgroups
    Goodman, Abigail
    Schniederjan, Matthew
    Mendoza, Pia
    Morales-Vargas, Bryan
    Neill, Stewart
    Velazquez-Vega, Jose
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2020, 79 (06): : 711 - 711
  • [50] Induction of lef1 during zebrafish fin regeneration
    Poss, KD
    Shen, JX
    Keating, MT
    DEVELOPMENTAL DYNAMICS, 2000, 219 (02) : 282 - 286