Tcf1 and Lef1 pack their own HDAC

被引：0
|
作者：
Charles P Ng
Dan R Littman
机构：
[1] Charles P. Ng is with The Kimmel Center for Biology and Medicine of the Skirball Institute,
[2] New York University School of Medicine,undefined
[3] New York,undefined
[4] New York,undefined
[5] USA.,undefined
[6] Dan R. Littman is with The Kimmel Center for Biology and Medicine of the Skirball Institute and the Howard Hughes Medical Institute,undefined
[7] New York University School of Medicine,undefined
[8] New York,undefined
[9] New York,undefined
[10] USA.,undefined
来源：
Nature Immunology | 2016年 / 17卷
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摘要：
The transcription factors Tcf1 and Lef1 have intrinsic histone-deacetylase activity that is required for the repression of CD4+ T cell–lineage genes in CD8+ T cells.
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页码：615 / 616
页数：1
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