Effects and cost-effectiveness of pharmacogenetic screening for CYP2D6 among older adults starting therapy with nortriptyline or venlafaxine: study protocol for a pragmatic randomized controlled trial (CYSCEtrial)

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作者
Elizabeth JJ Berm
Eelko Hak
Maarten Postma
Marjolein Boshuisen
Laura Breuning
Jacobus RBJ Brouwers
Ton Dhondt
Paul AF Jansen
Rob M Kok
Jan G Maring
Rob van Marum
Hans Mulder
Richard C Oude Voshaar
Arne J Risselada
Harry Venema
Liesbeth Vleugel
Bob Wilffert
机构
[1] Groningen Institute of Pharmacy,Department of Epidemiology
[2] University of Groningen,Departement of Old Age and Clinical Psychiatry
[3] Unit of Pharmacotherapy & Pharmaceutical Care,Department of Geriatric Medicine and Expertise Centere Pharmacotherapy in Old Persons
[4] Groningen Institute of Pharmacy,Department of Old
[5] University of Groningen,age Psychiatry
[6] Unit of Pharmacoepidemiology & Pharmacoeconomics,Department of Old Age
[7] University Medical Center Groningen,Laboratory for Drug Analysis & Toxicology
[8] Lentis,Department of Geriatric Medicine
[9] Dignis,Department of General Practice & Elderly Care Medicine
[10] Reinier van Arkel Group,Clinical Pharmacy
[11] UMC Utrecht,Department of Old Age Psychiatry
[12] GGZ-Noord Holland Noord,Department of Old Age Psychiatry
[13] Parnassia Psychiatric Institute,Department of Clinical Pharmacy and Pharmacology
[14] Diaconessen Hospital Meppel & Bethesda Hospital Hoogeveen,undefined
[15] Jeroen Bosch Hospital,undefined
[16] VU University,undefined
[17] Wilhelmina Hospital Assen,undefined
[18] University of Groningen,undefined
[19] University Medical Center Groningen,undefined
[20] University Center for Psychiatry,undefined
[21] GGZ Friesland,undefined
[22] GGZ inGeest,undefined
[23] University Medical Center Groningen,undefined
来源
Trials | / 16卷
关键词
CYP2D6; Pharmacogenetics; Depression; Nortriptyline; Venlafaxine;
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