A new 5H-purin-6-amine from the leaves of Sedum sarmentosum

被引:0
|
作者
Sunghun Cho
Jaemin Lee
Joyce P. Rodriguez
Buom-Yong Ryu
Chan Kyu Han
Sanghyun Lee
机构
[1] Chung-Ang University,Department of Integrative Plant Science
[2] Chung-Ang University,Department of Animal Science and Technology
[3] Korea Food Research Institute,undefined
来源
关键词
Chromatography; 5; -Purin-6-amine; Isolation;
D O I
暂无
中图分类号
学科分类号
摘要
Phytochemical constituents were isolated from Sedum sarmentosum leaves using open column chromatography and medium-pressure liquid chromatography. Their structures were identified as 2,4-pyrimidinedione (1), N-methylhydroxylamine (2), 5H-purin-6-amine (3), uridine (4), l-tyrosine (5), and l-prolyl-l-tyrosine (6) using mass spectrometry and 1H- and 13C-nuclear magnetic resonance spectroscopic analysis. Among them, compound 3 (5H-purin-6-amine) was isolated for the first time from a natural source.
引用
收藏
页码:109 / 111
页数:2
相关论文
共 50 条
  • [21] N-(2-Methoxybenzyl)-9-(oxolan-2-yl)-9H-purin-6-amine
    Travnicek, Zdenek
    Popa, Igor
    Dvorak, Zdenek
    Starha, Pavel
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O588 - +
  • [22] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 3,5-DINITRO-4-(1H-PURIN-6-YLTHIO)BENZOATES AND 5-DINITRO-2-(1H-PURIN-6-YLTHIO)BENZOATES, PRODRUGS OF 6-MERCAPTOPURINE
    DRAWBAUGH, R
    BOUFFARD, C
    STRAUSS, M
    JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (11) : 1342 - 1345
  • [23] 3H-[1,2,4]-Triazolo[5,1-i]purin-5-amine derivatives as adenosine A2A antagonists
    Silverman, Lisa S.
    Caldwell, John P.
    Greenlee, William J.
    Kiselgof, Eugenia
    Matasi, Julius J.
    Tulshian, Deen B.
    Arik, Leyla
    Foster, Carolyn
    Bertorelli, Rosalia
    Monopoli, Angela
    Ongini, Ennio
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (06) : 1659 - 1662
  • [24] FACILE SYNTHESIS OF 9H-S-TRIAZOLO[3,4-I]PURIN-5(6H)-ONES
    SHIMADA, J
    SUZUKI, F
    TETRAHEDRON LETTERS, 1992, 33 (22) : 3151 - 3154
  • [25] Bioactive constituents from Chinese natural medicines.: XXV.: New flavonol bisdesmosides, sarmenosides I, II, III, and IV, with hepatoprotective activity from Sedum sarmentosum (Crassulaceae)
    Zhang, Yi
    Morikawa, Toshio
    Nakamura, Seikou
    Ninomiya, Kiyofumi
    Matsuda, Hisashi
    Muraoka, Osamu
    Yoshikawa, Masayuki
    HETEROCYCLES, 2007, 71 (07) : 1565 - 1576
  • [26] 2-Methyl-5-nitro-1H-benzimidazol-6-amine dihydrate
    Dincer, Sebla
    Dal, Hakan
    Hokelek, Tuncer
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2490 - U1690
  • [27] Novel Products from C6H5 + C6H6/C6H5 Reactions
    Shukla, Bikau
    Tsuchiya, Kentaro
    Koshi, Mitsuo
    JOURNAL OF PHYSICAL CHEMISTRY A, 2011, 115 (21): : 5284 - 5293
  • [28] Synthesis of acyclic nucleoside and nucleotide analogs derived from 6-amino-7H-purin-8(9H)-one
    Janeba, Z
    Holy, A
    Masojídková, M
    COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 2000, 65 (07) : 1126 - 1144
  • [29] NEW METAL-BORANE ANION [(ETA-5-C5H5)NIB6H6]-
    VINITSKII, DM
    LAGUN, VL
    SOLNTSEV, KA
    KUZNETSOV, NT
    MARUSHKIN, KN
    YANOUSHEK, Z
    BASHE, K
    SHTIBR, B
    ZHURNAL NEORGANICHESKOI KHIMII, 1984, 29 (07): : 1714 - 1717
  • [30] An approach to the evaluation of the activity of the DNA repair enzyme O6-methylguanine-DNA-methyl-transferase in tumor tissue in vivo:: syntheses of 6-benzyloxy-9-(2-[18F]fluoroethyl)-9H-purin-2-yl-amine and 6-benzyloxy-7-(2-[18F]fluoroethyl)-7H-purin-2-yl-amine
    Schirrmacher, R
    Nesseler, E
    Hamkens, W
    Eichhorn, U
    Schreckenberger, M
    Kaina, B
    Rösch, F
    APPLIED RADIATION AND ISOTOPES, 2002, 56 (03) : 511 - 517