Optimization of conditions for the liquid chromatographic-electrospray lonization-mass spectrometric analysis of amnesic shellfish poisoning toxins

被引：0
|
作者：
N. Piñeiro
E. Vaquero
J. M. Leão
A. Gogo-Martínez
J. A. Rodríguez Vázquez
机构：
[1] Universidad de Vigo,Departamento de Química Analítica y Alimentaria
来源：
Chromatographia | 2001年 / 53卷
关键词：
Liquid chromatography-mass spectrometry; Amnesic shellfish poisoning toxins; Optimization of parameters;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In this paper we report results obtained from analysis of domoic acid and its analogues, toxins responsible for incidents of amnesic shellfish poisoning (ASP) in several places world-wide, by use of liquid chromatography coupled with electrospray ionization mass spectrometry. Different chromatographic and mass spectrometry conditions were evaluated with the aim of achieving the best chromatographic performance combined with the optimum mass spectrometric response. From the results obtained it can be concluded that LC-MS is powerful tool for the selective and sensitive determination of domoic acid and its isomers in naturally contaminated samples.
引用
收藏
页码：S231 / S235
相关论文
共 50 条
  • [31] A liquid chromatographic-electrospray ionization-tandem mass spectrometric method for determination of buprenorphine, its metabolite, norBuprenorphine, and a coformulant, naloxone, that is suitable for in vivo and in vitro metabolism studies
    Moody, DE
    Slawson, MH
    Strain, EC
    Laycock, JD
    Spanbauer, AC
    Foltz, RL
    ANALYTICAL BIOCHEMISTRY, 2002, 306 (01) : 31 - 39
  • [32] Electrospray-Mass Spectrometric Analysis of Plasma Pyrophosphates Separated on a Multi-Modal Liquid Chromatographic Column
    Lee, Su Hyeon
    Lee, Jeongae
    Lee, Won-Yong
    Chung, Bong Chul
    Choi, Man Ho
    MASS SPECTROMETRY LETTERS, 2011, 2 (04) : 92 - 95
  • [33] Phytogenic effects of Marrubium vulgare on the growth performance of weaned piglets: biochemical parameters and liquid chromatographic-electrospray ionization-mass spectrometric profile of plant and animal serum
    da Silva, Ana Caroline
    Da Cunha, Guinter Silva
    Tizziani, Tiago
    Schlemper, Valfredo
    Sandjo, Louis P.
    JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2024, 104 (15) : 9758 - 9771
  • [34] Optimization of Hydrophilic Interaction Liquid Chromatography/Mass Spectrometry and Development of Solid-Phase Extraction for the Determination of Paralytic Shellfish Poisoning Toxins
    Turrell, Elizabeth
    Stobo, Lesley
    Lacaze, Jean-Pierre
    Piletsky, Sergey
    Piletska, Elena
    JOURNAL OF AOAC INTERNATIONAL, 2008, 91 (06) : 1372 - 1386
  • [35] Ultra-performance liquid chromatographic-electrospray mass spectrometric determination (UPLC-ESI-MS) of protocatechuic aldehyde (3,4-dihydroxybenzaldehyde, PAL) glucuronidation in vitro
    Liu, Hui-Xin
    Hu, Ying
    Yang, Ling
    DRUG METABOLISM REVIEWS, 2009, 41 : 115 - 116
  • [36] Separation and purification of two minor typical diarrhetic shellfish poisoning toxins from harmful marine microalgae via combined liquid chromatography with mass spectrometric detection
    Chen, Junhui
    Wang, Yanlong
    Pan, Lei
    Shen, Huihui
    Fu, Dan
    Fu, Boqiang
    Sun, Chengjun
    Zheng, Li
    JOURNAL OF SEPARATION SCIENCE, 2017, 40 (14) : 2906 - 2913
  • [37] Liquid chromatography-electrospray ionization mass spectrometry of the diarrhetic shellfish-poisoning toxins okadaic acid, dinophysistoxin-1 and pectenotoxin-6 in bivalves
    Suzuki, T
    Yasumoto, T
    JOURNAL OF CHROMATOGRAPHY A, 2000, 874 (02) : 199 - 206
  • [38] High throughput analysis of amnesic shellfish poisoning toxins in bivalve molluscs by dispersive solid-phase extraction and high-performance liquid chromatography using a monolithic column
    Regueiro, Jorge
    Alvarez, Gonzalo
    Mauriz, Aida
    Blanco, Juan
    FOOD CHEMISTRY, 2011, 127 (04) : 1884 - 1891
  • [39] Analysis of diarrhetic shellfish poisoning toxins and pectenotoxin-2 in the bottlenose dolphin (Tursiops truncatus) by liquid chromatography-tandem mass spectrometry
    Wang, Zhihong
    Broadwater, Margaret H.
    Ramsdell, John S.
    JOURNAL OF CHROMATOGRAPHY A, 2015, 1416 : 22 - 30
  • [40] IONSPRAY MASS-SPECTROMETRY OF MARINE TOXINS .3. ANALYSIS OF PARALYTIC SHELLFISH POISONING TOXINS BY FLOW-INJECTION ANALYSIS, LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY AND CAPILLARY ELECTROPHORESIS MASS-SPECTROMETRY
    PLEASANCE, S
    AYER, SW
    LAYCOCK, MV
    THIBAULT, P
    RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1992, 6 (01) : 14 - 24
12345