Clinical islet cell transplantationAre we there yet?

被引:0
|
作者
Lawrence Rosenberg
机构
[1] McGill University,Department of Surgery and Medicine
[2] McGill University Health Centre,Centre for Pancreatic Diseases
[3] Montreal General Hospital,undefined
关键词
Diabetes mellitus; islet cell transplantation; DCCT; immunosuppression;
D O I
10.1007/BF02788418
中图分类号
学科分类号
摘要
Diabetes mellitus is perhaps the most devastating chronic disease of all time. A brief history of the evolution of treatment modalities is provided, culminating in the rationale for the physiologic replacement of a functioning β-cell mass by transplantation. Vascularized pancreas transplantation is discussed briefly as an introduction to the transplantation of the isolated islet. A detailed review of the current state of human islet transplantation for the cure of diabetes is then described. Finally, areas for future development are highlighted.
引用
收藏
页码:145 / 168
页数:23
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