N-Boc Protection of Amines Using Silica Propyl(N-methyl) Imidazolium Chloride as an Efficient and Reusable Catalyst

被引：0
|
作者：
Somaye Karimian
Hassan Tajik
机构：
[1] Persian Gulf University,Department of Chemistry
[2] Young Researchers and Elite Club,undefined
[3] Bushehr Branch,undefined
[4] Islamic Azad University,undefined
来源：
Iranian Journal of Science and Technology, Transactions A: Science | 2016年 / 40卷
关键词：
Silica-supported ionic liquid; Silica propyl(; -methyl) imidazolium chloride; -Boc protection; Tert-butoxycarbonylation; Amine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A simple and efficient method for the N-Boc protection of amines using (Boc)2O in the presence of a catalytic amount of silica propyl(N-methyl) imidazolium chloride ([Sipmim]Cl) is introduced. The catalyst was efficient and reusable for this process under solvent-free conditions at ambient temperature. This methodology has several advantages in comparison with currently used methods including high yields, simple workup procedure, short reaction time, and clean and mild reaction conditions.
引用
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页码：267 / 274
页数：7
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