Current role of LC-MS in therapeutic drug monitoring

被引：0
|
作者：
Franck Saint-Marcoux
François-Ludovic Sauvage
Pierre Marquet
机构：
[1] Limoges University Hospital,Department of Pharmacology
来源：
Analytical and Bioanalytical Chemistry | 2007年 / 388卷
关键词：
Therapeutic drug monitoring; Liquid chromatography; Mass spectrometry;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The role of liquid chromatography coupled with mass spectrometry (LC-MS) techniques in routine therapeutic drug monitoring activity is becoming increasingly important. This paper reviews LC-MS methods published in the last few years for certain classes of drugs subject to therapeutic drug monitoring: immunosuppressants, antifungal drugs, antiretroviral drugs, antidepressants and antipsychotics. For each class of compounds, we focussed on the most interesting methods and evaluated the current role of LC-MS in therapeutic drug monitoring.
引用
收藏
页码：1327 / 1349
页数：22
相关论文
共 50 条
  • [31] Simultaneous Quantification of Nine Antimicrobials by LC-MS/MS for Therapeutic Drug Monitoring in Critically Ill Patients
    Neugebauer, Sophie
    Wichmann, Christina
    Bremer-Streck, Sibylle
    Hagel, Stefan
    Kiehntopf, Michael
    THERAPEUTIC DRUG MONITORING, 2019, 41 (01) : 29 - 37
  • [32] Potential pitfalls in LC-MS/MS quantification of colistin for therapeutic drug monitoring of patients treated with colistimethate
    Barco, Sebastiano
    Castagnola, Elio
    Mesini, Alessio
    Tripodi, Gino
    Cangemi, Giuliana
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 170 : 193 - 195
  • [33] A LC-MS/MS method for therapeutic drug monitoring of sorafenib, regorafenib and their active metabolites in patients with hepatocellular carcinoma
    Iacuzzi, Valentina
    Zanchetta, Martina
    Gagno, Sara
    Poetto, Ariana Soledad
    Orleni, Marco
    Marangon, Elena
    Guardascione, Michela
    Foltran, Luisa
    Posocco, Bianca
    Toffoli, Giuseppe
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 187
  • [34] A rapid, simple and sensitive LC-MS/MS method for lenvatinib quantification in human plasma for therapeutic drug monitoring
    Zanchetta, Martina
    Iacuzzi, Valentina
    Posocco, Bianca
    Bortolin, Giorgia
    Poetto, Ariana Soledad
    Orleni, Marco
    Canil, Giovanni
    Guardascione, Michela
    Foltran, Luisa
    Fanotto, Valentina
    Puglisi, Fabio
    Gagno, Sara
    Toffoli, Giuseppe
    PLOS ONE, 2021, 16 (10):
  • [35] Easy and fast LC-MS/MS determination of lidocaine and MEGX in plasma for therapeutic drug monitoring in neonates with seizures
    ter Weijden, E.
    van den Broek, M. P. H.
    Ververs, F. F. T.
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 881-82 : 111 - 114
  • [36] An LC-MS/MS Method for Absolute Quantification of Nivolumab in Human Plasma: Application to Clinical Therapeutic Drug Monitoring
    Irie, Kei
    Okada, Akira
    Yamasaki, Yuta
    Kokan, Chiyuki
    Hata, Akito
    Kaji, Reiko
    Fukushima, Keizo
    Sugioka, Nobuyuki
    Okada, Yutaka
    Katakami, Nobuyuki
    Fukushima, Shoji
    THERAPEUTIC DRUG MONITORING, 2018, 40 (06) : 716 - 724
  • [37] Innovative LC-MS/MS method for therapeutic drug monitoring of fenfluramine and cannabidiol in the plasma of pediatric patients with epilepsy
    Pigliasco, Federica
    Cafaro, Alessia
    Barco, Sebastiano
    Stella, Manuela
    Mattioli, Francesca
    Riva, Antonella
    Mancardi, Maria Margherita
    Lattanzi, Simona
    Bandettini, Roberto
    Striano, Pasquale
    Cangemi, Giuliana
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 245
  • [38] Routine therapeutic drug monitoring of tyrosine kinase inhibitors by HPLC-UV or LC-MS/MS methods
    Miura, Masatomo
    Takahashi, Naoto
    DRUG METABOLISM AND PHARMACOKINETICS, 2016, 31 (01) : 12 - 20
  • [39] Ultra-fast LC-MS/MS in therapeutic drug monitoring: Quantification of clozapine and norclozapine in human plasma
    Couchman, Lewis
    Fisher, Danielle S.
    Subramaniam, Krithika
    Handley, Simon A.
    Boughtflower, Robert J.
    Benton, Christopher M.
    Flanagan, Robert J.
    DRUG TESTING AND ANALYSIS, 2018, 10 (02) : 323 - 329
  • [40] Development and validation of an integrated LC-MS/MS assay for therapeutic drug monitoring of five PARP-inhibitors
    Bruin, M. A. C.
    de Vries, N.
    Lucas, L.
    Rosing, H.
    Huitema, A. D. R.
    Beijnen, J. H.
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 1138 (1138):
12345