Current role of LC-MS in therapeutic drug monitoring

被引：0
|
作者：
Franck Saint-Marcoux
François-Ludovic Sauvage
Pierre Marquet
机构：
[1] Limoges University Hospital,Department of Pharmacology
来源：
Analytical and Bioanalytical Chemistry | 2007年 / 388卷
关键词：
Therapeutic drug monitoring; Liquid chromatography; Mass spectrometry;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The role of liquid chromatography coupled with mass spectrometry (LC-MS) techniques in routine therapeutic drug monitoring activity is becoming increasingly important. This paper reviews LC-MS methods published in the last few years for certain classes of drugs subject to therapeutic drug monitoring: immunosuppressants, antifungal drugs, antiretroviral drugs, antidepressants and antipsychotics. For each class of compounds, we focussed on the most interesting methods and evaluated the current role of LC-MS in therapeutic drug monitoring.
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页码：1327 / 1349
页数：22
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