The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways

被引：0
|
作者：
Igor Hrgovic
Monika Doll
Johannes Kleemann
Xiao-Fan Wang
Nadja Zoeller
Andreas Pinter
Stefan Kippenberger
Roland Kaufmann
Markus Meissner
机构：
[1] Venereology and Allergology,Department of Dermatology
[2] Goethe University,Department of Pharmacology & Cancer Biology
[3] Duke University School of Medicine,undefined
[4] Klinik für Dermatologie,undefined
[5] Venerologie und Allergologie,undefined
[6] Klinikum der J. W. Goethe-Universität,undefined
来源：
BMC Cancer | / 16卷
关键词：
Histon deacetylase inhibitors (HDACi); Lymphangiogenesis; G0/G1 cell cycle arrest; p21; intrinsic apoptotic pathway;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Histone deacetylase inhibitor induces cell apoptosis and cycle arrest in lung cancer cells via mitochondrial injury and p53 up-acetylation
    Bao, Lianmin
    Diao, Hua
    Dong, Nian
    Su, Xiaoqiong
    Wang, Bingbin
    Mo, Qiongya
    Yu, Heguo
    Wang, Xiangdong
    Chen, Chengshui
    CELL BIOLOGY AND TOXICOLOGY, 2016, 32 (06) : 469 - 482
  • [22] Histone deacetylase inhibitor (Trichostatin A) inhibits vascular smooth muscle cells proliferation via upregulation of cyclin dependent kinase inhibitor p21waf1
    Okamoto, H
    Taniguchi, T
    Takahashi, A
    Takahashi, T
    Takaishi, H
    Takahashi, Y
    Matsuo, Y
    Yamadori, T
    Ninomiya, K
    Kamemura, K
    Ishikawa, Y
    CIRCULATION, 2002, 106 (19) : 18 - 18
  • [23] P21-dependent G1arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228
    V Sandor
    A Senderowicz
    S Mertins
    D Sackett
    E Sausville
    M V Blagosklonny
    S E Bates
    British Journal of Cancer, 2000, 83 : 817 - 825
  • [24] Cell cycle blockade and differentiation of ovarian cancer cells by the histone deacetylase inhibitor trichostatin A are associated with changes in p21, Rb, and Id proteins
    Strait, KA
    Dabbas, B
    Hammond, EH
    Warnick, CT
    Ilstrup, SJ
    Ford, CD
    MOLECULAR CANCER THERAPEUTICS, 2002, 1 (13) : 1181 - 1190
  • [25] The histone deacetylase inhibitor panobinostat exerts anticancer effects on esophageal squamous cell carcinoma cells by inducing cell cycle arrest
    Cheng, Yin-Wei
    Liao, Lian-Di
    Yang, Qian
    Chen, Yang
    Nie, Ping-Juan
    Zhang, Xiao-Jun
    Xie, Jian-Jun
    Shan, Bao-En
    Zhao, Lian-Mei
    Xu, Li-Yan
    Li, En-Min
    CELL BIOCHEMISTRY AND FUNCTION, 2018, 36 (08) : 398 - 407
  • [26] A natural histone deacetylase inhibitor, Psammaplin A, induces cell cycle arrest and apoptosis in human endometrial cancer cells
    Ahn, Mee Young
    Jung, Jee H.
    Na, Yong Jin
    Kim, Hyung Sik
    GYNECOLOGIC ONCOLOGY, 2008, 108 (01) : 27 - 33
  • [27] DEAD-box protein 21 promotes renal fibrosis via p21-dependent cell cycle arrest in proximal tubular epithelial cells
    Tian, Maoqing
    Wang, Xiaofei
    Zhang, Meng
    Li, Chen
    Xu, Yuhan
    Chen, Xinghua
    Chen, Cheng
    Wei, Zhongping
    Li, Xiaoyan
    Ding, Guohua
    Zhang, Lu
    Wang, Huiming
    Gan, Hua
    CELLULAR SIGNALLING, 2025, 128
  • [28] Regulation of the cell cycle by metformin is p21-dependent in lung cancer
    Templeton, Amanda
    Ramesh, Rajagopal
    CANCER RESEARCH, 2014, 74 (19)
  • [29] Histone deacetylase inhibitor trichostatin A induced caspase-independent apoptosis in human gastric cancer cell
    Center of Cancer Therapy
    中华医学杂志(英文版), 2007, (23) : 2112 - 2118
  • [30] Histone deacetylase inhibitor trichostatin A induced caspase-independent apoptosis in human gastric cancer cell
    Wu Zhi-qun
    Zhang Rui
    Connie Chao
    Zhang Ji-feng
    Zhang Yuan-qiang
    CHINESE MEDICAL JOURNAL, 2007, 120 (23) : 2112 - 2118
12345