Next-generation algorithms for neoantigen selection

被引：0
|
作者：
Alexander Hopkins
Elizabeth Jaffee
机构：
[1] Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins,
来源：
Nature Reviews Gastroenterology & Hepatology | 2018年 / 15卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Predicting clinical outcomes in cancer using neoantigen burden is imperfect because current algorithms use only the binding affinity of putative neoantigens to HLA. A new study models pancreatic tumour response through a deeper understanding of tumour immunology, providing new tools for identifying neoantigens and characteristics that define their quality.
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页码：135 / 136
页数：1
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