A first-in-man study of [18F] FEDAC: a novel PET tracer for the 18-kDa translocator protein

被引：0
|
作者：
Kentaro Tamura
Ryuichi Nishii
Kotaro Tani
Hiroki Hashimoto
Kazunori Kawamura
Ming-Rong Zhang
Takamasa Maeda
Kana Yamazaki
Tatsuya Higashi
Masahiro Jinzaki
机构：
[1] National Institutes for Quantum Science and Technology (QST),Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate
[2] Keio University School of Medicine,Department of Radiology
[3] Nagoya University,Department of Integrated Health Sciences, Graduate School of Medicine
[4] National Institutes for Quantum Science and Technology (QST),Department of Radiation Measurement and Dose Assessment, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate
[5] National Institutes for Quantum Science and Technology (QST),Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate
[6] QST Hospital,Department of Medical Technology, Quantum Life and Medical Science Directorate
[7] National Institutes for Quantum Science and Technology (QST),undefined
来源：
Annals of Nuclear Medicine | 2024年 / 38卷
关键词：
Translocator Protein; TSPO; Normal healthy volunteers; Positron emission tomography; Biodistribution; Radiation Dosimetry; IDAC;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：264 / 271
页数：7
相关论文
共 50 条
  • [41] Novel [18F]fluoroethoxy- and [18F]fluoropropoxyindoleacetamides for imaging the TSPO 18kDa (PBR) with PET
    Damont, Annelaure
    Catarina, Tony
    Kuhnast, Bertrand
    Boisgard, Raphael
    Marguet, Frank
    Puech, Frederic
    Rooney, Thomas
    Tavitian, Bertrand
    Dolle, Frederic
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2011, 54 : S34 - S34
  • [42] The Functionality of 18-kda Translocator Protein Radioligand [18F] GE-180 as a Biomarker in the Diagnostic and Prognostic Evaluation of Spinal Cord Injury Imaging
    Cha, S.
    Doig, R. O'Hare
    Guerrero, K.
    Bartholomeusz, D.
    INTERNAL MEDICINE JOURNAL, 2022, 52 : 20 - 20
  • [43] Whole Body Biodistribution and Radiation Dosimetry in Humans of a New PET Ligand, [18F]-FEPPA, to Image Translocator Protein (18 kDa)
    Romina Mizrahi
    Pablo M. Rusjan
    Irina Vitcu
    Alvina Ng
    Alan A. Wilson
    Sylvain Houle
    Peter M. Bloomfield
    Molecular Imaging and Biology, 2013, 15 : 353 - 359
  • [44] In vivo Evaluation of Inflammatory Bowel Disease with the Aid of μPET and the Translocator Protein 18 kDa Radioligand [18F]DPA-714
    Bernards, Nicholas
    Pottier, Geraldine
    Theze, Benoit
    Dolle, Frederic
    Boisgard, Raphael
    MOLECULAR IMAGING AND BIOLOGY, 2015, 17 (01) : 67 - 75
  • [45] Neuroinflammation in Major Depressive Disorder: A Review of PET Imaging Studies Examining the 18-kDa Translocator Protein
    Gritti, Davide
    Delvecchio, Giuseppe
    Ferro, Adele
    Bressi, Cinzia
    Brambilla, Paolo
    JOURNAL OF AFFECTIVE DISORDERS, 2021, 292 : 642 - 651
  • [46] Whole Body Biodistribution and Radiation Dosimetry in Humans of a New PET Ligand, [18F]-FEPPA, to Image Translocator Protein (18 kDa)
    Mizrahi, Romina
    Rusjan, Pablo M.
    Vitcu, Irina
    Ng, Alvina
    Wilson, Alan A.
    Houle, Sylvain
    Bloomfield, Peter M.
    MOLECULAR IMAGING AND BIOLOGY, 2013, 15 (03) : 353 - 359
  • [47] In vivo Evaluation of Inflammatory Bowel Disease with the Aid of μPET and the Translocator Protein 18 kDa Radioligand [18F]DPA-714
    Nicholas Bernards
    Géraldine Pottier
    Benoit Thézé
    Frédéric Dollé
    Raphael Boisgard
    Molecular Imaging and Biology, 2015, 17 : 67 - 75
  • [48] Design, Synthesis, and Biological Evaluation of Novel Fluorescent Probes Targeting the 18-kDa Translocator Protein
    Wongso, Hendris
    Yamasaki, Tomoteru
    Kumata, Katsushi
    Ono, Maiko
    Higuchi, Makoto
    Zhang, Ming-Rong
    Fulham, Michael J.
    Katsifis, Andrew
    Keller, Paul A.
    CHEMMEDCHEM, 2021, 16 (12) : 1902 - 1916
  • [49] Synthesis and evaluation of two novel 18F-labeled acetamidobenzoxazolone radioligands for PET imaging of translocator protein (18 kDa)
    Tiwari, Anjani K.
    Fujinaga, Masayuki
    Kumata, Katsushi
    Shimoda, Yoko
    Yui, Joji
    Yamasaki, Tomoteru
    Xie, Lin
    Hatori, Akiko
    Ogawa, Masanao
    Kawamura, Kazunori
    Zhang, Ming-Rong
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2015, 58 : S154 - S154
  • [50] Conditional Knockout of the Mitochondrial 18-kDa Translocator Protein Limits Heart Failure
    Phung Thai
    Lu, Xiyuan
    Daugherty, Daniel
    Deng, Wenbin
    Bers, Donald M.
    Schaefer, Saul
    CIRCULATION, 2015, 132
12345