The pedunculopontine nucleus as a target for deep brain stimulation

被引：0
|
作者：
Clement Hamani
Elena Moro
Andres M. Lozano
机构：
[1] University of Toronto,Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network
[2] University of Toronto,Division of Neurology, Department of Medicine, Toronto Western Hospital, University Health Network
来源：
Journal of Neural Transmission | 2011年 / 118卷
关键词：
Pedunculopontine nucleus; Parkinson’s disease; Surgery; Deep brain stimulation; Gait; Falls; Sleep;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The pedunculopontine nucleus (PPN) is a brain stem locomotive center that is also involved in the processing of sensory and behavioral information. The PPN has been recently proposed as a potential target for the treatment of axial symptoms in Parkinson’s disease (PD). To date, results of the first series of PD patients treated with PPN deep brain stimulation (DBS) have shown promising results. In this article, we review some of the basic aspects of the PPN as a target and the outcome of the recently published clinical trials.
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页码：1461 / 1468
页数：7
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