FLIP-mediated autophagy regulation in cell death control

被引：0
|
作者：
Jong-Soo Lee
Qinglin Li
June-Yong Lee
Sun-Hwa Lee
Joseph H. Jeong
Hye-Ra Lee
Heesoon Chang
Fu-Chun Zhou
Shou-Jiang Gao
Chengyu Liang
Jae U. Jung
机构：
[1] University of Southern California,Department of Molecular Microbiology and Immunology
[2] Keck School of Medicine,Department of Microbiology and Molecular Genetics and Tumour Virology Division
[3] Harlyne J. Norris Cancer Research Tower,Department of Pediatrics
[4] New England Primate Research Center,Department of Cancer Immunology and AIDS, Dana
[5] Harvard Medical School,Farber Cancer Institute and the Department of Pathology
[6] The University of Texas Health Science Center at San Antonio,undefined
[7] Harvard Medical School,undefined
来源：
Nature Cell Biology | 2009年 / 11卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Two inhibitors of death receptor-associated apoptosis, cellular c-FLIP and viral v-FLIP prevents LC3 processing by Atg3 and thus repress the autophagic cell death that follows mTOR inhibition. Short peptides derived from FLIP can prevent Atg3–FLIP interaction without affecting Atg3–LC3, restoring cell death.
引用
收藏
页码：1355 / 1362
页数：7
相关论文
共 50 条
  • [21] Autophagy and cell death
    Gozuacik, Devrim
    Kimchi, Adi
    CURRENT TOPICS IN DEVELOPMENTAL BIOLOGY, VOL 78, 2007, 78 : 217 - 245
  • [22] Autophagy and cell death
    Yonekawa, Tohru
    Thorburn, Andrew
    AUTOPHAGY: MOLECULES AND MECHANISMS, 2013, 55 : 105 - 117
  • [23] Autophagy and cell death
    Fulda, S.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : S10 - S11
  • [24] Cell death and autophagy
    Uchiyama, Yasuo
    AUTOPHAGY, 2009, 5 (06) : 912 - 912
  • [25] Cell death and autophagy
    Uchiyama, Yasuo
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010, 60 : S22 - S22
  • [26] Chemotherapy and autophagy-mediated cell death in pancreatic cancer cells
    Ropolo, Alejandro
    Bagnes, Claudia I.
    Molejon, Maria I.
    Lo Re, Andrea
    Boggio, Veronica
    Gonzalez, Claudio D.
    Vaccaro, Maria I.
    PANCREATOLOGY, 2012, 12 (01) : 1 - 7
  • [27] Role of Autophagy Dysfunction on Propofol-Mediated Cell Proliferation or Death
    Wang, Yong
    Xu, Zhendong
    Liang, Ge
    Liu, Zhiqiang
    Ma, Wuhua
    Ward, Christopher
    Wei, Huafeng
    ANESTHESIA AND ANALGESIA, 2017, 124 : 639 - 639
  • [28] UTX coordinates steroid hormone-mediated autophagy and cell death
    Denton, Donna
    Aung-Htut, May T.
    Lorensuhewa, Nirmal
    Nicolson, Shannon
    Zhu, Wenying
    Mills, Kathryn
    Cakouros, Dimitrios
    Bergmann, Andreas
    Kumar, Sharad
    NATURE COMMUNICATIONS, 2013, 4
  • [29] Selenium nanoparticles induce autophagy mediated cell death in human keratinocytes
    Kirwale, Shrikant
    Pooladanda, Venkatesh
    Thatikonda, Sowjanya
    Murugappan, Sivasubramanian
    Khurana, Amit
    Godugu, Chandraiah
    NANOMEDICINE, 2019, 14 (15) : 1991 - 2010
  • [30] UTX coordinates steroid hormone-mediated autophagy and cell death
    Donna Denton
    May T. Aung-Htut
    Nirmal Lorensuhewa
    Shannon Nicolson
    Wenying Zhu
    Kathryn Mills
    Dimitrios Cakouros
    Andreas Bergmann
    Sharad Kumar
    Nature Communications, 4
12345