T follicular helper and B cell crosstalk in tertiary lymphoid structures and cancer immunotherapy

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作者
Soizic Garaud
Marie-Caroline Dieu-Nosjean
Karen Willard-Gallo
机构
[1] Université Libre de Bruxelles,Molecular Immunology Laboratory, Institut Jules Bordet
[2] Sorbonne University UMRS1135,undefined
[3] Inserm U1135,undefined
[4] Laboratory “Immune microenvironment and immunotherapy”,undefined
[5] Centre d’Immunologie et des Maladies Infectieuses Paris (CIMI-Paris),undefined
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Tumor-infiltrating lymphocytes (TILs) are critical in the elimination of cancer cells, a concept highlighted by recent advances in cancer immunotherapy. Significant evidence reveals that their organization in tertiary lymphoid structures together with specific subpopulation composition/balances stimulates cellular crosstalk and anti-tumor immunity in patients.
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