A new deal for Holliday junctions

被引：0
|
作者：
Wolf-Dietrich Heyer
机构：
[1] Section of Microbiology and Section of Molecular and Cellular Biology,Division of Biological Sciences
[2] and Center for Genetics and Development,undefined
[3] University of California,undefined
来源：
Nature Structural & Molecular Biology | 2004年 / 11卷
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学科分类号：
摘要：
BLM, the helicase implicated in Bloom's syndrome, and its yeast counterpart Sgs1 function in complexes with a type I topoisomerase to resolve double Holliday junctions to form non-crossover products. These data provide a direct explanation for the highly elevated sister chromatid exchange frequency in Bloom's syndrome cells.
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页码：117 / 119
页数：2
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